Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31754646 | 0.84 | KDM4E (0.41) | DRD4SIGMAR1USP30KDM4ELMNA | |
| SCHEMBL8488039 | 0.76 | SIGMAR1 (0.53) | DRD4SIGMAR1KDM4ELMNAPOLB | |
| SCHEMBL17677243 | 0.76 | SIGMAR1 (0.50) | DRD4SIGMAR1KDM4ELMNACYP1A2 | |
| SCHEMBL31754727 | 0.76 | HRH3 (0.42) | USP30CDK12KDM4ELMNACYP1A2 | |
| SCHEMBL31754616 | 0.75 | TRPV1 (0.44) | — | |
| SCHEMBL25124555 | 0.73 | SIGMAR1 (0.60) | DRD4SIGMAR1KDM4ELMNACYP1A2 | |
| SCHEMBL12100560 | 0.72 | ALDH1A1 (0.59) | DRD4SIGMAR1ALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL30097493 | 0.72 | ALDH1A1 (0.59) | DRD4SIGMAR1ALDH1A1SMN1; SMN2AOC3 | |
| SCHEMBL14890550 | 0.71 | TDO2 (0.51) | DRD4SIGMAR1ALDH1A1 | |
| SCHEMBL18382209 | 0.71 | DRD4 (0.46) | DRD4SIGMAR1KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260000692-A1 | Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors | AURIGENE ONCOLOGY LIMITED (IN) | 2026-01-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260000692-A1 | Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors | CDK1, CDK12, CDK11A | DRD4 4750/4885SIGMAR1 3414/4885USP30 3419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.