SCHEMBL3176335

SCHEMBL3176335

CCc1cc(OP(=O)(O)O)c(-c2ccccc2)c(CC)c1CC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 9/20 0.40
KDM4E B2RXH2 1/20 0.40
USP2 O75604 1/20 0.40
ALDH1A1 P00352 1/20 0.40
HPGD P15428 1/20 0.40
PDE3A Q14432 1/20 0.40
HSD17B10 Q99714 1/20 0.40
SRC P12931 2/20 0.39
INPP5A Q14642 4/20 0.38
INPP5B P32019 2/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
GPR84 Q9NQS5 1/20 0.36
PTPN5 P54829 1/20 0.36
AKT1 P31749 1/20 0.35
GCGR P47871 1/20 0.34
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FABP3 P05413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL446046 0.84 KDM4E (0.41) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL29493895 0.84 KDM4E (0.41) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL11805355 0.80 ALDH1A1 (0.40) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL30725926 0.79 GPR84 (0.41) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL9579203 0.77 ALDH1A1 (0.40) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL717618 0.77 GPR84 (0.40) INPPL1KDM4EUSP2ALDH1A1HPGD
Biphenyl SCHEMBL28005747 0.75 HSD17B10 (0.50) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL444782 0.75 KDM4E (0.38) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL448371 0.73 GCGR (0.40) INPPL1KDM4EUSP2ALDH1A1HPGD
SCHEMBL382005 0.72 INPPL1 (0.48) INPPL1KDM4EUSP2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US claimed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US claimed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US claimed
US-7651827-B2 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION (US) 2010-01-26 US disclosed
US-7527902-B2 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION (US) 2009-05-05 US disclosed
US-20070026328-A1 Photoreceptor layer having phosphorus-containing lubricant XEROX CORPORATION 2007-02-01 US disclosed
US-20070026330-A1 Photoreceptor layer having solid and liquid lubricants XEROX CORPORATION 2007-02-01 US disclosed
US-6586376-B1 Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2003-07-01 US disclosed
US-6511947-B1 A mixture of a polyphenyl ether having 4-5 aromatic rings and/or its hydrocarbon substituted group with a polyphenyl thioether having 3-5 aromatic rings, an amine antioxidant, a phosphate, and an amine salt of acid phosphate TONEN GENERAL SEKIYU K.K. (JP) 2003-01-28 US disclosed
US-6191080-B1 MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS TONEN CORPORATION (JP) 2001-02-20 US disclosed