SCHEMBL3176375

SCHEMBL3176375

CC(C)(C)[Si](OC(=O)CCCCCCC(=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.42
HDAC4 P56524 2/20 0.42
HDAC1 Q13547 2/20 0.42
HDAC7 Q8WUI4 2/20 0.42
HDAC2 Q92769 2/20 0.42
HDAC10 Q969S8 2/20 0.42
HDAC11 Q96DB2 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
HDAC6 Q9UBN7 2/20 0.42
HDAC9 Q9UKV0 2/20 0.42
HDAC5 Q9UQL6 2/20 0.42
MAPT P10636 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
NPSR1 Q6W5P4 1/20 0.39
TBXAS1 P24557 5/20 0.38
MAPK1 P28482 1/20 0.38
ADRA1A P35348 1/20 0.38
SLC6A3 Q01959 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PTGIR P43119 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663589 0.95 TSHR (0.41) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL6545076 0.91 KDM4E (0.36) MAPTSMN1; SMN2ALDH1A1
SCHEMBL6376734 0.90 CES2 (0.44)
SCHEMBL6656947 0.89 NR4A2 (0.38) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL4644925 0.88 CYP4F2 (0.35) MAPTSMN1; SMN2VCAM1ALDH1A1PPARA
SCHEMBL29072114 0.88 CES2 (0.43)
SCHEMBL6546547 0.88 CYP2C19 (0.35) MAPTSMN1; SMN2ALDH1A1
SCHEMBL4641886 0.87 SMN1; SMN2 (0.35) HDAC1HDAC2SMN1; SMN2LTB4RALDH1A1
SCHEMBL4641522 0.87 KDM4E (0.34) MAPTSMN1; SMN2VCAM1ALDH1A1PPARA
SCHEMBL30116362 0.87 KDM4E (0.46) NPSR1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7645614-B2 Method of immobilizing compound on solid phase support REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) 2010-01-12 US disclosed
US-7645614-B2 Method of immobilizing compound on solid phase support REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD. (JP) 2010-01-12 US disclosed
US-20060024845-A1 Method of immobilizing compound on solid phase support REVERSE PROTEOMICS RESEARCH INSTITUTE CO., LTD (JP) 2006-02-02 US disclosed
EP-1564555-A1 METHOD OF IMMOBILIZING COMPOUND ON SOLID PHASE SUPPORT Reverse Proteomics Research Institute Co., Ltd (JP) 2005-08-17 EP disclosed