Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546547 | 0.95 | CYP2C19 (0.35) | CYP2C19HIF1AALDH1A1GAALMNA | |
| SCHEMBL6663589 | 0.91 | TSHR (0.41) | CYP2C19HIF1ABLMCYP2D6ALDH1A1 | |
| SCHEMBL3176375 | 0.89 | HDAC3 (0.42) | ALDH1A1SMN1; SMN2HDAC6NPSR1HDAC3 | |
| SCHEMBL6545076 | 0.89 | KDM4E (0.36) | CYP2C19HIF1AALDH1A1GAALMNA | |
| SCHEMBL4644661 | 0.87 | CYP2C19 (0.33) | CYP2C19HIF1AALDH1A1 | |
| SCHEMBL4643575 | 0.86 | CYP2C19 (0.32) | CYP2C19HIF1AALDH1A1 | |
| SCHEMBL4644075 | 0.86 | HIF1A (0.32) | CYP2C19HIF1AALDH1A1MAPK1 | |
| SCHEMBL6072563 | 0.85 | CYP2C19 (0.37) | CYP2C19HIF1ASMN1; SMN2RBP4 | |
| SCHEMBL6072557 | 0.85 | ABL1 (0.35) | CYP2C19HIF1ALMNASMN1; SMN2HDAC6 | |
| SCHEMBL5844438 | 0.84 | SLC15A1 (0.36) | NR4A2CYP2C19HIF1ABLMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |