Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6663589 | 0.95 | TSHR (0.41) | CYP2C19HIF1AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6546547 | 0.93 | CYP2C19 (0.35) | KDM4EMEN1KMT2ALMNACYP2C19 | |
| SCHEMBL27601469 | 0.93 | HPGD (0.34) | KDM4EMEN1RECQLKMT2AADRB2 | |
| SCHEMBL4641522 | 0.92 | KDM4E (0.34) | KDM4EMEN1RECQLKMT2AADRB2 | |
| SCHEMBL30116362 | 0.92 | KDM4E (0.46) | KDM4EMEN1RECQLKMT2ATOP2A | |
| SCHEMBL4642010 | 0.91 | ALDH1A1 (0.35) | KDM4EMEN1RECQLKMT2AADRB2 | |
| SCHEMBL3176375 | 0.91 | HDAC3 (0.42) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL4647018 | 0.91 | PRSS1 (0.34) | KDM4EMEN1RECQLKMT2AADRB2 | |
| SCHEMBL29072114 | 0.91 | CES2 (0.43) | KDM4EMEN1RECQLKMT2ALMNA | |
| SCHEMBL4644925 | 0.91 | CYP4F2 (0.35) | KDM4EMEN1RECQLKMT2AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004005302-A1 | PROCESS FOR THE PREPARATION OF ACYLOXYSILANES | SIGMA COATINGS B.V. (NL) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378514-A1 | Process for the preparation of acyloxysilanes | SigmaKalon Group B.V. (NL) | 2004-01-07 | — | — | EP | disclosed |