Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020845 | 0.78 | GPR3 (0.68) | GPR3KDM4ESMN1; SMN2PDPK1CA12 | |
| SCHEMBL29421129 | 0.72 | PARP1 (0.55) | GPR3KDM4ESMN1; SMN2PDPK1CA12 | |
| Phenanthridine SCHEMBL30823553 | 0.71 | GPR3 (1.00) | GPR3KDM4ESMN1; SMN2PDPK1ERN1 | |
| Phenanthridine SCHEMBL9106884 | 0.71 | GPR3 (1.00) | GPR3KDM4ESMN1; SMN2PDPK1ERN1 | |
| Phenanthridine SCHEMBL30914262 | 0.71 | GPR3 (1.00) | GPR3KDM4ESMN1; SMN2PDPK1ERN1 | |
| Phenanthridine SCHEMBL8666 | 0.71 | GPR3 (1.00) | GPR3KDM4ESMN1; SMN2PDPK1ERN1 | |
| SCHEMBL17498089 | 0.71 | MAPT (0.50) | KDM4ESMN1; SMN2ALOX15PAX8MAPT | |
| SCHEMBL8525477 | 0.71 | PARP1 (0.46) | GPR3KDM4ESMN1; SMN2PDPK1CA12 | |
| Phenanthridine SCHEMBL23003530 | 0.70 | GPR3 (0.95) | GPR3KDM4ESMN1; SMN2PDPK1ERN1 | |
| SCHEMBL2231455 | 0.70 | KDM4E (0.68) | GPR3KDM4EERN1MAPTNCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375038-A | Preparation method of dibenzozepine | 山东嘉成医药科技有限公司 | 2021-02-19 | — | — | CN | claimed |
| EP-2164830-B1 | PROCESS FOR THE PREPARATION OF DIBENZO [B,D]AZEPIN-6-ONE DERIVATIVE | HOFFMANN LA ROCHE (CH) | 2013-05-29 | — | — | EP | claimed |
| US-7579464-B2 | Process for preparation of enantiomerically pure compounds | HOFFMANN-LA ROCHE INC. (US) | 2009-08-25 | — | — | US | claimed |
| US-20080293933-A1 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE COMPOUNDS | HOFFMANN-LA ROCHE, INC. | 2008-11-27 | — | — | US | claimed |
| EP-1633348-B1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARM INC (US) | 2008-10-08 | — | — | EP | claimed |
| US-20060281733-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carvoxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | ELAN PHARMACEUTICALS, INC. | 2006-12-14 | — | — | US | claimed |
| EP-1633348-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B sb 1 /sb RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Elan Pharmaceuticals, Inc. (US) | 2006-03-15 | — | — | EP | claimed |
| US-20050020659-A1 | Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | ELAN PHARMACEUTICALS, INC. | 2005-01-27 | — | — | US | claimed |
| WO-2004098589-A1 | 4- BROMO - 5 - (2- CHLORO - BENZOYLAMINO) - 1H - PYRAZOLE - 3 - CARBOXYLIC ACID AMIDE DERIVATIVES AND RELATED COMPOUNDS AS BRADYKININ B1 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | ELAN PHARMACEUTICALS, INC. (US) | 2004-11-18 | — | — | WO | claimed |
| EP-1093372-A4 | CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARM INC (US) | 2004-09-29 | — | — | EP | claimed |
| EP-0713093-B1 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER AG (US) | 2001-10-10 | — | — | EP | claimed |
| EP-1093372-A1 | CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 2001-04-25 | — | — | EP | claimed |
| WO-1999066934-A1 | CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | claimed |
| EP-0698600-B1 | Composition, method and test device for determining the presence of leukocyte cells, esterase or protease in a test sample | BAYER AG (US) | 1999-11-10 | — | — | EP | claimed |
| CN-122036610-A | Synthesis method of central chiral aza seven-membered bridged aromatic compound containing chiral axis | 浙江大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20260097047-A1 | Small molecule inhibitors of the ribosome biogenesis factor NVL2 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2026-04-09 | — | — | US | disclosed |
| US-20260097047-A1 | Small molecule inhibitors of the ribosome biogenesis factor NVL2 | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2026-04-09 | — | — | US | disclosed |
| US-4434100-A | TRANQUILIZING, ANTICONVULSANTS, ANXIOLYTIC | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4356176-A | TRANQUILIZERS, ANTICONVULSANT | CIBA-GEIGY CORPORATION (US) | 1982-10-26 | — | — | US | disclosed |
| US-4315926-A | ANXIOLYTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020659-A1 | Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists | BDKRB1, BDKRB2, BRS3 | GPR3 197/4885KDM4E 4503/4885SMN1; SMN2 3553/4885 |
| US-20080293933-A1 | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE COMPOUNDS | BACE1, BACE2, BCHE | GPR3 1558/4885KDM4E 477/4885SMN1; SMN2 2294/4885 |
| US-20260097047-A1 | Small molecule inhibitors of the ribosome biogenesis factor NVL2 | NOC2L, RPS6, RPS3A | GPR3 2998/4885KDM4E 2720/4885SMN1; SMN2 2686/4885 |
| US-20060281733-A1 | 4-Bromo-5-(2-chloro-benzoylamino)-1h-pyrazole-3-carvoxylic acid amide derivatives and related compounds as bradykinin b1 receptor antagonists for the treatment of inflammatory diseases | BDKRB1, BDKRB2, CNR1 | GPR3 76/4885KDM4E 2152/4885SMN1; SMN2 3662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.