Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.38 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997404 | 0.72 | ALDH1A1 (0.50) | KDM4EGPR3NCF1PI4KAPI4K2B | |
| SCHEMBL3179065 | 0.71 | GPR3 (0.56) | PARP1KDM4EGPR3NCF1PI4KA | |
| SCHEMBL14678 | 0.71 | CYP1A2 (0.57) | KDM4EGPR3SMN1; SMN2PDPK1CA12 | |
| SCHEMBL29418017 | 0.71 | CYP1A2 (0.57) | KDM4EGPR3SMN1; SMN2PDPK1CA12 | |
| Hydrochloric Acid SCHEMBL8324913 | 0.69 | CYP1A2 (0.55) | KDM4EGPR3SMN1; SMN2PDPK1CA12 | |
| Hydrochloric Acid SCHEMBL29862578 | 0.69 | CYP1A2 (0.55) | KDM4EGPR3SMN1; SMN2PDPK1CA12 | |
| Hydrochloric Acid SCHEMBL7362443 | 0.69 | CYP1A2 (0.55) | KDM4EGPR3SMN1; SMN2PDPK1CA12 | |
| SCHEMBL25245129 | 0.69 | PDGFRB (0.51) | KDM4EGPR3NCF1PI4KAPI4K2B | |
| SCHEMBL29990013 | 0.69 | NR4A2 (0.41) | KDM4EGPR3SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28495811 | 0.69 | BACE1 (0.47) | KDM4EGPR3NCF1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977355-A | Processes and intermediates for preparing 3-amino-benzo(b)azepinones | PFIZER INC. (US) | 1999-11-02 | — | — | US | disclosed |