Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 17/20 | 0.49 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3170801 | 0.96 | S1PR1 (0.52) | ESR2ESR1S1PR1ABHD6 | |
| SCHEMBL3171285 | 0.84 | ESR2 (0.57) | ESR2ESR1S1PR1 | |
| SCHEMBL12408702 | 0.81 | ESR2 (0.67) | ESR2ESR1ABHD6 | |
| SCHEMBL3176570 | 0.80 | ABHD6 (0.47) | ESR2ESR1S1PR1ABHD6 | |
| SCHEMBL14116816 | 0.80 | S1PR1 (0.48) | S1PR1ABHD6 | |
| SCHEMBL3181247 | 0.77 | ESR1 (0.47) | ESR2ESR1S1PR1 | |
| SCHEMBL3178592 | 0.76 | GPR119 (0.55) | ESR2ESR1ABHD6 | |
| SCHEMBL3192125 | 0.76 | ESR1 (0.45) | ESR2ESR1S1PR1 | |
| SCHEMBL2177564 | 0.76 | ABHD6 (0.50) | ESR2ESR1S1PR1ABHD6 | |
| SCHEMBL3176556 | 0.75 | GPR119 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2010-01-28 | — | — | US | disclosed |
| EP-2114890-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008097428-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022515-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GCGR, GPR65 | ESR2 218/4885ESR1 638/4885S1PR1 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.