SCHEMBL6364875

SCHEMBL6364875

CCc1ccc2[nH]nnc2c1.[Ag]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.36
KIF11 P52732 1/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
SMN1; SMN2 Q16637 4/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.36
MEN1 O00255 2/20 0.36
GAA P10253 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 1/20 0.36
PTK2B Q14289 1/20 0.36
TRPA1 O75762 1/20 0.35
HTR1A P08908 2/20 0.35
HTR1D P28221 2/20 0.35
HTR1B P28222 2/20 0.35
ELANE P08246 2/20 0.35
MAPK10 P53779 1/20 0.35
RIPK1 Q13546 1/20 0.35
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241363 0.98 TP53 (0.37) TP53KIF11NPC1RAB9ASMN1; SMN2
SCHEMBL27708683 0.96 TP53 (0.36) TP53KIF11NPC1RAB9ASMN1; SMN2
SCHEMBL241224 0.84 CNR1 (0.39) NPC1RAB9AHTR1AHTR1DMAPT
SCHEMBL318089 0.83 KIF11 (0.41) TP53KIF11NPC1RAB9ASMN1; SMN2
SCHEMBL6365081 0.83 HTR1A (0.40) TP53NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL501616 0.82 MEN1 (0.39) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL242265 0.81 HTR1A (0.41) TP53NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28419742 0.80 HTR1A (0.40) TP53NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL242143 0.80 HTR1A (0.43) TP53RAB9AALDH1A1LMNAHTR1A
SCHEMBL30387310 0.80 HTR1A (0.40) TP53NPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101130549-A Antimicrobial NIPPON CHEMICAL INDUSTRY CO LT (JP) 2008-02-27 CN disclosed
US-6890705-B2 Silver halide photosensitive material and image-forming method using same FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 US disclosed
US-20030118952-A1 Silver halide photosensitive material and image-forming method using same FUJI PHOTO FILM CO., LTD. 2003-06-26 US disclosed