Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238856 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL9225490 | 0.77 | KDM4E (0.46) | ALDH1A1SMN1; SMN2KDM4ELMNASLC1A3 | |
| SCHEMBL9652726 | 0.77 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL9001208 | 0.77 | SLC1A3 (0.55) | ALDH1A1TDP1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL27339112 | 0.77 | MEN1 (0.55) | ALDH1A1TDP1TSHRKDM4ELMNA | |
| SCHEMBL1027277 | 0.76 | CA1 (0.63) | ALDH1A1TDP1SMN1; SMN2LMNAGAA | |
| SCHEMBL23175141 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL3192320 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL7515257 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL11749464 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRSMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674936-B2 | Ortho-substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-03-09 | — | — | US | disclosed |
| CN-100528862-C | Ortho-substituted aryl amide compounds for controlling invertebrate pests | DU PONT (US) | 2009-08-19 | — | — | CN | disclosed |
| EP-1423379-B1 | ORTHO-SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | DU PONT (US) | 2008-05-28 | — | — | EP | disclosed |
| US-7288554-B2 | Ortho-substituted aryl amides for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-30 | — | — | US | disclosed |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | FMC CORPORATION | 2007-10-25 | — | — | US | disclosed |
| CN-1865258-A | Ortho-substituted aryl amides for controlling invertebrate pests | DU PONT (US) | 2006-11-22 | — | — | CN | disclosed |
| CN-1549811-A | Ortho-substituted aryl amide compounds for controlling invertebrate pests | ��Ļ���Ű˾ | 2004-11-24 | — | — | CN | disclosed |
| US-20040192731-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192731-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | DDT, ACHE, CBR1 | ALDH1A1 819/4885TDP1 2975/4885TSHR 1430/4885 |
| US-20070249832-A1 | Ortho-substituted aryl amides for controlling invertebrate pests | NR2C2, GRK6, NR0B2 | ALDH1A1 3071/4885TDP1 4686/4885TSHR 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.