Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 14/20 | 0.63 |
| ▸ | CCKAR | P32238 | 11/20 | 0.63 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.60 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.59 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643277 | 0.93 | CCKBR (0.68) | CCKBRCCKARBDKRB1 | |
| SCHEMBL643033 | 0.93 | CCKBR (0.71) | CCKBRCCKAR | |
| SCHEMBL16110814 | 0.81 | CCKBR (0.64) | CCKBRCCKAR | |
| SCHEMBL643974 | 0.80 | CHRM1 (0.65) | CCKBRCCKARBDKRB1 | |
| SCHEMBL642974 | 0.80 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL12214184 | 0.80 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL29766969 | 0.80 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL18394863 | 0.80 | CCKBR (0.76) | CCKBRCCKAR | |
| SCHEMBL18394473 | 0.80 | CCKBR (0.76) | CCKBRCCKAR | |
| SCHEMBL2930364 | 0.80 | CCKBR (0.76) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100015063-A1 | Benzodiazepine Derivatives and Pharmaceutical Compositions Containing Them | ARROW THERAPEUTICS LIMITED (GB) | 2010-01-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100015063-A1 | Benzodiazepine Derivatives and Pharmaceutical Compositions Containing Them | GABRA6, CNR1, SIGMAR1 | CCKBR 197/4885CCKAR 137/4885BDKRB1 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.