SCHEMBL3185508

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5422761	0.94	EPHX2 (0.60)	EPHX2NR1H4NR1I2SERPINE1KCNQ3
	SCHEMBL3210134	0.90	EPHX2 (0.55)	EPHX2NR1H4NR1I2SERPINE1KCNQ3
	SCHEMBL3195444	0.89	NR1I2 (0.63)	EPHX2NR1H4NR1I2SERPINE1KCNQ3
	SCHEMBL3198691	0.89	EPHX2 (0.51)	EPHX2NR1H4NR1I2SERPINE1KCNQ3
	SCHEMBL3195396	0.86	NR1I2 (0.54)	EPHX2NR1H4NR1I2SERPINE1KCNQ3
	SCHEMBL3204698	0.85	NR1I2 (0.53)	EPHX2NR1H4NR1I2SERPINE1ALDH1A1
	SCHEMBL3183923	0.85	CRHBP (0.47)	EPHX2NR1H4NR1I2SERPINE1KCNQ3
	SCHEMBL3205119	0.84	NR1I2 (0.51)	EPHX2NR1H4NR1I2SERPINE1KCNQ3
	SCHEMBL28771625	0.83	EPHX2 (0.56)	EPHX2NR1H4NR1I2KCNQ3KCNQ2
	SCHEMBL5418798	0.80	SERPINE1 (0.56)	EPHX2NR1I2SERPINE1ALOX5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.