SCHEMBL3187404

SCHEMBL3187404

O=C(O)c1ccc(Oc2ccc(C3(c4ccc(Oc5ccc(C(=O)O)cc5)cc4)c4cc(C56CC7CC(CC(C7)C5)C6)ccc4-c4cc(Cl)c(C56CC7CC(CC(C7)C5)C6)c(Cl)c43)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 2/20 0.39
HIF1A Q16665 3/20 0.38
EPAS1 Q99814 2/20 0.38
IKBKB O14920 4/20 0.37
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
THRB P10828 1/20 0.36
RECQL P46063 1/20 0.36
NR2E1 Q9Y466 1/20 0.36
RARA P10276 7/20 0.35
RARB P10826 6/20 0.35
RARG P13631 6/20 0.35
MDH1 P40925 1/20 0.35
MDH2 P40926 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2707835 0.86 HIF1A (0.45) SERPINE1HIF1AEPAS1IKBKBMEN1
SCHEMBL3175819 0.86 RXRA (0.37) IKBKBRARBRARGCYP3A4RXRA
Hydrochloric Acid SCHEMBL3187412 0.85 HIF1A (0.44) SERPINE1HIF1AEPAS1IKBKBMEN1
Hydrochloric Acid SCHEMBL3187397 0.85 HIF1A (0.44) SERPINE1HIF1AEPAS1IKBKBMEN1
SCHEMBL2710161 0.79 RARB (0.48) SERPINE1HIF1AEPAS1IKBKBMEN1
SCHEMBL2707905 0.77 HIF1A (0.42) SERPINE1HIF1AEPAS1MEN1KMT2A
SCHEMBL2707997 0.75 POLB (0.41) SERPINE1HIF1AEPAS1MEN1KMT2A
SCHEMBL19362904 0.75 MEN1 (0.55) SERPINE1HIF1AEPAS1MEN1KMT2A
SCHEMBL2706995 0.73 EPHX2 (0.42) HIF1AEPAS1IKBKBMEN1KMT2A
SCHEMBL2708821 0.73 RXRA (0.46) RARARARBRARGCYP3A4RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7863347-B2 Resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2011-01-04 US disclosed
US-7652125-B2 Resin composition, polyimide resin composition, polybenzoxazole resin composition, varnish, resin film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2010-01-26 US disclosed
US-20080255335-A1 Resin Composition, Polyimide Resin Composition, Polybenzoxazole Resin Composition, Varnish, Resin Film and Semiconductor Device Using the Same SUMITOMO BAKELITE COMPANY LTD. (JP) 2008-10-16 US disclosed
EP-1813637-A1 RESIN COMPOSITION, POLYIMIDE RESIN COMPOSITION, POLY- BENZOXAZOLE RESIN COMPOSITION, VARNISHES, RESIN FILMS AND SEMICONDUCTOR DEVICES MADE BY USING THE SAME Sumitomo Bakelite Company, Limited (JP) 2007-08-01 EP disclosed