Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.63 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8433610 | 0.82 | TRPA1 (0.52) | CSNK2A1TRPA1TP53TDP1ALOX15 | |
| SCHEMBL11044723 | 0.80 | CSNK2A1 (0.55) | CSNK2A1TRPA1TP53TDP1ALOX15 | |
| SCHEMBL29740060 | 0.77 | CSNK2A1 (1.00) | CSNK2A1TRPA1TDP1ALOX15HSD17B10 | |
| SCHEMBL127149 | 0.77 | CSNK2A1 (1.00) | CSNK2A1TRPA1TDP1ALOX15HSD17B10 | |
| SCHEMBL10702551 | 0.77 | CSNK2A1 (0.52) | CSNK2A1TRPA1TP53TDP1ALOX15 | |
| SCHEMBL10373446 | 0.77 | CSNK2A1 (0.52) | CSNK2A1TRPA1TP53TDP1ALOX15 | |
| SCHEMBL6715407 | 0.76 | CA12 (0.60) | ALOX15HSD17B10ALDH1A1LMNAMEN1 | |
| Ammonia Solution, Strong SCHEMBL25338596 | 0.76 | CSNK2A1 (0.96) | CSNK2A1TRPA1TDP1ALOX15HSD17B10 | |
| SCHEMBL18741297 | 0.76 | CSNK2A1 (0.96) | CSNK2A1TDP1ALOX15HSD17B10ALDH1A1 | |
| SCHEMBL18741295 | 0.76 | CSNK2A1 (0.96) | CSNK2A1TRPA1TDP1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109899-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-04 | — | — | US | disclosed |
| CN-1872846-B | Method of preparing 2-benzothiazepines derivative | UBE INDUSTRIES | 2010-06-16 | — | — | CN | disclosed |
| US-7671195-B2 | Process for preparing dibenzothiazepine compounds | ASTRAZENECA UK LIMITED (GB) | 2010-03-02 | — | — | US | disclosed |
| CN-100577653-C | Process for preparing dibenzothiazepine derivatives | UBE INDUSTRIES | 2010-01-06 | — | — | CN | disclosed |
| US-7576241-B2 | Derivatives of amidines, their preparation, their use as medicaments and the pharmaceutical compositions containing them | IPSEN PHARMA S.A.S. (FR) | 2009-08-18 | — | — | US | disclosed |
| CN-101389615-A | Process for preparing dibenzothiazepine compounds | ASTRAZENECA UK LTD UBE IND (GB) | 2009-03-18 | — | — | CN | disclosed |
| US-7473779-B2 | Derivatives of amidines, their preparation, their use as medicaments and the pharmaceutical compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2009-01-06 | — | — | US | disclosed |
| EP-1996568-A2 | PROCESS FOR PREPARING DIBENZOTHIAZEPINE COMPOUNDS | AstraZeneca UK Limited (GB) | 2008-12-03 | — | — | EP | disclosed |
| US-7314930-B2 | Process for preparing dibenzothiazepine derivatives | UBE INDUSTRIES, LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| WO-2007102352-A2 | PROCESS FOR PREPARING DIBENZOTHIAZEPINE COMPOUNDS | ASTRAZENECA UK LIMITED (GB) | 2007-09-13 | — | — | WO | disclosed |
| CN-85109587-A | Have the new benzothiophene kind of antiallergic activity and the preparation method of benzofuran compounds | — | 1986-12-17 | — | — | CN | disclosed |
| EP-0187487-A1 | Benzothiophenes and benzofurans having antiallergic activity | WARNER-LAMBERT COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |
| EP-0005607-B1 | XANTHONE AND THIOXANTHONE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KEFALAS A/S (DK) | 1983-10-26 | — | — | EP | disclosed |
| EP-0026000-B1 | SPIRO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Takeda Chemical Industries, Ltd. (JP) | 1983-05-11 | — | — | EP | disclosed |
| US-4362740-A | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-12-07 | — | — | US | disclosed |
| US-4285956-A | NEUROLEPTIC AND ANTICHOLENERGIC AGENTS; PSYCHOLOGICAL DISORDERS INCLUDING SCHIZOPHRENIA; ANTIEMETIC AGENTS | KEFALAS A/S (DK) | 1981-08-25 | — | — | US | disclosed |
| US-4275209-A | NEUROLEPTIC AND ANTIEMETIC ACTIVITY FOR TREATMENT OF PSYCHOLOGICAL DISORDERS | KEFALAS A/S (DK) | 1981-06-23 | — | — | US | disclosed |
| EP-0026000-A1 | Spiro compounds, process for their preparation and pharmaceutical compositions containing them | Takeda Chemical Industries, Ltd. (JP) | 1981-04-01 | — | — | EP | disclosed |
| EP-0005607-A1 | Xanthone and thioxanthone derivatives, their preparation and pharmaceutical compositions containing them | KEFALAS A/S (DK) | 1979-11-28 | — | — | EP | disclosed |
| US-4006243-A | FUNGICIDE, BACTERICIDE, YEAST | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109899-A1 | BENZOFURAN COMPOUNDS AS STING AGONISTS | STING1, MAVS, IRF3 | CSNK2A1 2453/4885TRPA1 42/4885TP53 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.