Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344234 | 0.70 | CYP1A2 (0.39) | MEN1KMT2AATMTSHRHTT | |
| SCHEMBL22644428 | 0.70 | ALDH1A1 (0.37) | GAA | |
| SCHEMBL9383601 | 0.70 | CCNA2 (0.35) | MAPT | |
| SCHEMBL10447738 | 0.70 | ALDH1A1 (0.37) | — | |
| SCHEMBL33145 | 0.69 | ALDH1A1 (0.43) | MEN1KMT2AATMTSHRHTT | |
| SCHEMBL18783521 | 0.69 | MEN1 (0.34) | MEN1KMT2AATMTSHRHTT | |
| SCHEMBL138352 | 0.69 | HSD17B10 (0.44) | MEN1KMT2AATMTSHRHTT | |
| SCHEMBL1576395 | 0.69 | TSHR (0.44) | MEN1KMT2AATMTSHRHTT | |
| SCHEMBL21936016 | 0.69 | TP53 (0.31) | TSHRHTTTP53POLBGAA | |
| SCHEMBL10604745 | 0.69 | CCNA2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741294-B1 | Non-standard nucleobases implementing the isocytidine and isoguanosine hydrogen bonding patterns | BENNER STEVEN ALBERT | 2010-06-22 | — | — | US | disclosed |
| US-7741294-B1 | Non-standard nucleobases implementing the isocytidine and isoguanosine hydrogen bonding patterns | BENNER STEVEN ALBERT | 2010-06-22 | — | — | US | disclosed |
| US-7666851-B1 | Three ring fused analogs of isoguanosine | BENNER STEVEN ALBERT | 2010-02-23 | — | — | US | disclosed |
| US-7666851-B1 | Three ring fused analogs of isoguanosine | BENNER STEVEN ALBERT | 2010-02-23 | — | — | US | disclosed |