Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.37 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.37 |
| ▸ | ITGAL | P20701 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791513 | 0.86 | GAA (0.47) | CES2CES1ITGB2ICAM1ITGAL | |
| Thiourea SCHEMBL6832788 | 0.76 | CES2 (0.46) | CES2CES1CTSLMAOBMAPT | |
| SCHEMBL203321 | 0.74 | CES2 (0.64) | CES2CES1LMNAITGB2ICAM1 | |
| SCHEMBL20560251 | 0.74 | CES2 (0.50) | CES2CES1CTSLLMNAMEN1 | |
| SCHEMBL2031677 | 0.74 | PPP5C (0.42) | CES2CES1CTSLMAOBKMT2A | |
| SCHEMBL14333527 | 0.74 | CES2 (0.50) | CES2CES1LMNAITGB2ICAM1 | |
| SCHEMBL6503374 | 0.73 | CES2 (0.56) | CES2CES1CTSLMAOBMAPT | |
| SCHEMBL5529438 | 0.72 | ALDH1A1 (0.53) | CES2CES1LMNAITGB2ICAM1 | |
| SCHEMBL2031274 | 0.72 | CES2 (0.52) | CES2CES1CTSLLMNAMAOB | |
| Hydrochloric Acid SCHEMBL320643 | 0.72 | CES2 (0.48) | CES2CES1LMNAITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606263-B | Fluorine-containing benzothiazole diester compound and application thereof | 青岛科技大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-119707763-A | Method for synthesizing thioamide | 广东莱佛士制药技术有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-116606263-A | Fluorine-containing benzothiazole diester compound and application thereof | 青岛科技大学 | 2023-08-18 | — | — | CN | disclosed |
| US-9173883-B2 | Ring-substituted N-pyridinyl amides as kinase inhibitors | NOVARTIS AG (CH) | 2015-11-03 | — | — | US | disclosed |
| US-20150150873-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | NOVARTIS VACCINES AND DIAGNOSTICS, INC. | 2015-06-04 | — | — | US | disclosed |
| US-20150133473-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-05-14 | — | — | US | disclosed |
| EP-2861585-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | Novartis AG (CH) | 2015-04-22 | — | — | EP | disclosed |
| US-8987457-B2 | Ring-substituted N-pyridinyl amides as kinase inhibitors | NOVARTIS AG (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8829193-B2 | PIM kinase inhibitors and methods of their use | NOVARTIS AG (CH) | 2014-09-09 | — | — | US | disclosed |
| US-8829193-B2 | PIM kinase inhibitors and methods of their use | NOVARTIS AG (CH) | 2014-09-09 | — | — | US | disclosed |
| EP-1124827-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-22 | — | — | EP | disclosed |
| EP-1123281-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED CYCLOPROPYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| US-6262305-B1 | Process and intermediates for preparing 3-(substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds | DOW AGROSCIENCES LLC | 2001-07-17 | — | — | US | disclosed |
| US-6262099-B1 | USEFUL AS INSECTICIDES AND ACARICIDES. | DOW AGROSCIENCES LLC | 2001-07-17 | — | — | US | disclosed |
| EP-1113004-A2 | Intermediates for producing 3-(substituted phenyl)-5-(thienyl or furyl)-1,2,4-triazole compounds | Dow Agrosciences LLC (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000024720-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED CYCLOPROPYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
| WO-2000024739-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
| US-6015826-A | INSECTICIDES, APHIDICIDES, AND MITICIDES | DOW AGROSCIENCES LLC | 2000-01-18 | — | — | US | disclosed |
| EP-0922043-A1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | Dow AgroSciences LLC (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998047894-A1 | PESTICIDAL 3-(SUBSTITUTED PHENYL)-5-(THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC (US) | 1998-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133473-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | PIM1, PIM2, MAP3K1 | CES2 2803/4885CES1 1581/4885CTSL 3824/4885 |
| US-20150150873-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | PIM1, PIM2, MAP3K1 | CES2 2803/4885CES1 1581/4885CTSL 3824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.