Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14283951 | 0.92 | HDAC1 (0.59) | ACHEHDAC1HDAC6HDAC8HDAC3 | |
| SCHEMBL16494456 | 0.91 | ALOX5 (0.51) | ACHEADRB3ADRB2ADRB1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL16495178 | 0.90 | ALOX5 (0.50) | ACHEADRB3ADRB2ADRB1SIGMAR1 | |
| SCHEMBL4975930 | 0.88 | CHRM2 (0.56) | ACHEADRB3ADRB2ADRB1HDAC1 | |
| SCHEMBL31476393 | 0.84 | ADRB3 (0.52) | ACHEADRB3ADRB2ADRB1HDAC1 | |
| SCHEMBL8118083 | 0.82 | ADRB3 (0.50) | ACHEADRB3ADRB2ADRB1HDAC1 | |
| SCHEMBL28301164 | 0.82 | ADRB3 (0.50) | ACHEADRB3ADRB2ADRB1HDAC1 | |
| SCHEMBL29880799 | 0.82 | ADRB3 (0.50) | ACHEADRB3ADRB2ADRB1HDAC1 | |
| SCHEMBL9204870 | 0.82 | ADRB3 (0.50) | ACHEADRB3ADRB2ADRB1HDAC1 | |
| SCHEMBL15332179 | 0.82 | ADRB3 (0.50) | ACHEADRB3ADRB2ADRB1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655801-B2 | Substituted carbamic acid quinolin-6-yl esters useful as acetylcholinesterase inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-02-02 | — | — | US | disclosed |
| EP-1831172-B1 | SUBSTITUTED CARBAMIC ACID QUINOLIN-6-YL ESTERS USEFUL AS ACETYLCHOLINESTERASE INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2009-02-18 | — | — | EP | disclosed |
| EP-1831172-A1 | SUBSTITUTED CARBAMIC ACID QUINOLIN-6-YL ESTERS USEFUL AS ACETYLCHOLINESTERASE INHIBITORS | Council of Scientific and Industrial Research (IN) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006070394-A1 | SUBSTITUTED CARBAMIC ACID QUINOLIN-6-YL ESTERS USEFUL AS ACETYLCHOLINESTERASE INHIBITORS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-07-06 | — | — | WO | disclosed |
| US-20060142335-A1 | Substituted carbamic acid quinolin-6-yl esters useful as acetylcholinesterase inhibitors | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142335-A1 | Substituted carbamic acid quinolin-6-yl esters useful as acetylcholinesterase inhibitors | ACHE, BCHE, NAAA | ACHE 1/4885ADRB3 1783/4885ADRB2 2357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.