Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467328 | 0.85 | MDM2 (0.35) | MDM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL4059082 | 0.81 | MDM2 (0.41) | MDM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL2761711 | 0.77 | MEN1 (0.32) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL8855149 | 0.74 | MEN1 (0.35) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL322239 | 0.74 | MEN1 (0.35) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL2479674 | 0.74 | MDM2 (0.36) | MDM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL29947384 | 0.72 | IDO1 (0.44) | MDM2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL9957877 | 0.71 | KDM4E (0.46) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL4714608 | 0.68 | CASP3 (0.44) | KDM4ENPC1MAPTRAB9A | |
| SCHEMBL2122583 | 0.68 | NPC1 (0.45) | MDM2KDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100022568-A1 | ENDOTHELIN RECEPTOR ANTAGONISTS FOR EARLY STAGE IDIOPATHIC PULMONARY FIBROSIS | Actelion Pharmaceeuticals Ltd. (CH) | 2010-01-28 | — | — | US | disclosed |