SCHEMBL3190533

SCHEMBL3190533

[CH2]C[Si](C)(C)OCCOC(=O)C(=C)C

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.52
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.41
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10397319 0.87 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3181433 0.85 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL322653 0.82 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL679847 0.82 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL63712 0.82 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL65533 0.80 THRB (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6142874 0.79 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15636 0.79 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL13129202 0.79 THRB (0.58) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11806859 0.78 THRB (0.61) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662473-B2 Amorphous inorganic ceramic material and method of producing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-02-16 US disclosed
EP-1900710-A1 Method of producing inorganic molded item, and inorganic molded item obtained using the method Shin-Etsu Chemical Co., Ltd. (JP) 2008-03-19 EP disclosed
US-20080057816-A1 Silicone-based fiber, nonwoven fabric formed therefrom, and methods of producing same SHIN-ETSU CHEMICAL CO., LTD. 2008-03-06 US disclosed
US-20080053153-A1 Method of producing inorganic molded item, and inorganic molded item obtained using the method SHIN-ETSU CHEMICAL CO., LTD. 2008-03-06 US disclosed
US-20080057817-A1 Amorphous inorganic ceramic material and method of producing same SHIN-ETSU CHEMICAL CO., LTD. 2008-03-06 US disclosed
US-20080053051-A1 Method of producing heat-resistant inorganic textile and heat-resistant inorganic textile produced using the method SHIN-ETSU CHEMICAL CO., LTD. 2008-03-06 US disclosed
EP-1895032-A2 Silicone-based fiber, nonwoven fabric formed therefrom, and methods of producing same Shin-Etsu Chemical Co., Ltd. (JP) 2008-03-05 EP disclosed
EP-1894904-A1 Amorphous inorganic ceramic material and method of producing same Shin-Etsu Chemical Co., Ltd. (JP) 2008-03-05 EP disclosed
EP-1894902-A2 Method of producing heat-resistant inorganic textile and heat-resistant inorganic textile produced using the method Shin-Etsu Chemical Co., Ltd. (JP) 2008-03-05 EP disclosed