SCHEMBL322653

SCHEMBL322653

C=C(C)C(=O)OCCO[Si](C)(C)OCCOC(=O)C(=C)C

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.57
TSHR P16473 4/20 0.50
ALDH1A1 P00352 3/20 0.44
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
HTT P42858 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129202 0.92 THRB (0.58) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL679847 0.88 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL63712 0.88 THRB (0.57) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL19588493 0.86 THRB (0.51) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL65533 0.85 THRB (0.59) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL18470686 0.84 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6142874 0.84 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL15636 0.84 THRB (0.74) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10397319 0.84 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11806859 0.82 THRB (0.61) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4413085-A1 SILICON-AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES Arkema, Inc. (US) 2024-08-14 EP claimed
CN-118318010-A Coupling agents containing silicon and zinc for cellulosic material-polymer composites 阿科玛股份有限公司 2024-07-09 CN claimed
WO-2023059592-A1 SILICON-AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES ARKEMA INC. (US) 2023-04-13 WO claimed
CN-112739782-B Insulating coating composition for electrical steel sheet and electrical steel sheet having insulating coating POSCO公司 2022-04-26 CN claimed
WO-2020027545-A1 INSULATING COATING COMPOSITION FOR ELECTRICAL STEEL SHEET, AND ELECTRICAL STEEL SHEET COMPRISING INSULATING COATING 주식회사 포스코 2020-02-06 WO claimed
WO-2019034597-A1 FORCE-RESPONSIVE POLYMERSOMES AND NANOREACTORS; PROCESSES UTILIZING THE SAME ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2019-02-21 WO claimed
US-20070281870-A1 Stimuli-degradable gels HALLIBURTON ENERGY SERVICES, INC. 2007-12-06 US claimed
CN-114453217-B Insulating coating composition for electrical steel sheet and electrical steel sheet having insulating coating POSCO公司 2024-08-23 CN disclosed
EP-4413085-A1 SILICON-AND ZINC-CONTAINING COUPLING AGENT FOR CELLULOSIC MATERIAL-POLYMER COMPOSITES Arkema, Inc. (US) 2024-08-14 EP disclosed
CN-118318010-A Coupling agents containing silicon and zinc for cellulosic material-polymer composites 阿科玛股份有限公司 2024-07-09 CN disclosed
US-20240189417-A1 SUBSTITUTION OF NUCLEOTIDE BASES IN SELF-AMPLIFYING MESSENGER RIBONUCLEIC ACIDS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-06-13 US disclosed
CN-118043466-A Substitution of nucleotide bases in self-amplified mRNA 葛兰素史克生物有限公司 2024-05-14 CN disclosed
US-20240059846-A1 REACTIVE MICROPARTICLES AND THEIR USE TO PREPARE FUNCTIONAL HYDROGEL PARTICLES ALLARTA LIFE SCIENCE INC (CA) 2024-02-22 US disclosed
WO-2009132206-A1 COMPOSITIONS AND METHODS FOR INTRACELLULAR DELIVERY AND RELEASE OF CARGO LIQUIDIA TECHNOLOGIES, INC. (US) 2009-10-29 WO disclosed
US-7306040-B1 Stimuli-degradable gels HALLIBURTON ENERGY SERVICES, INC. (US) 2007-12-11 US disclosed
US-7306040-B1 Stimuli-degradable gels HALLIBURTON ENERGY SERVICES, INC. (US) 2007-12-11 US disclosed
US-20070277981-A1 STIMULI-DEGRADABLE GELS HALLIBURTON ENERGY SERVICES, INC. 2007-12-06 US disclosed
US-20070277981-A1 STIMULI-DEGRADABLE GELS HALLIBURTON ENERGY SERVICES, INC. 2007-12-06 US disclosed
US-20070281870-A1 Stimuli-degradable gels HALLIBURTON ENERGY SERVICES, INC. 2007-12-06 US disclosed
US-20070281870-A1 Stimuli-degradable gels HALLIBURTON ENERGY SERVICES, INC. 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189417-A1 SUBSTITUTION OF NUCLEOTIDE BASES IN SELF-AMPLIFYING MESSENGER RIBONUCLEIC ACIDS NSUN2, NSUN3, RNMT THRB 2709/4885TSHR 2502/4885ALDH1A1 3328/4885
US-20240059846-A1 REACTIVE MICROPARTICLES AND THEIR USE TO PREPARE FUNCTIONAL HYDROGEL PARTICLES LTA, VCL, HBB THRB 2111/4885TSHR 4092/4885ALDH1A1 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.