Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CD81 | P60033 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2211209 | 0.81 | CD81 (0.45) | CD81ATMALDH1A1MEN1KMT2A | |
| SCHEMBL12512540 | 0.81 | CD81 (0.36) | TRPA1CD81 | |
| SCHEMBL2210551 | 0.80 | POLB (0.37) | TRPA1CD81ATMALDH1A1MEN1 | |
| SCHEMBL13796849 | 0.78 | TRPA1 (0.36) | TRPA1 | |
| SCHEMBL13795718 | 0.78 | LMNA (0.43) | TRPA1ALDH1A1MEN1KMT2A | |
| SCHEMBL12511580 | 0.77 | HTT (0.39) | TRPA1CD81CYP3A4TSHRALDH1A1 | |
| SCHEMBL13796891 | 0.77 | GLA (0.38) | TRPA1CD81L3MBTL1TSHRMEN1 | |
| SCHEMBL13796893 | 0.75 | EPHX2 (0.34) | TRPA1ALDH1A1 | |
| SCHEMBL21446949 | 0.74 | TRPA1 (0.35) | TRPA1CD81ALDH1A1 | |
| SCHEMBL4298030 | 0.73 | ATM (0.38) | ATML3MBTL1CYP3A4TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678757-B2 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20090062405-A1 | CYCLOPROPANECARBOXALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-03-05 | — | — | US | disclosed |
| US-7491688-B2 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7491688-B2 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7491688-B2 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-20080026979-A1 | Cyclopropancarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-01-31 | — | — | US | disclosed |
| US-20080026979-A1 | Cyclopropancarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-01-31 | — | — | US | disclosed |
| US-20080026979-A1 | Cyclopropancarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2008-01-31 | — | — | US | disclosed |
| US-7271294-B2 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-7271294-B2 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-7271294-B2 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20060287557-A1 | CYCLOPROPANECARBOXALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2006-12-21 | — | — | US | disclosed |
| US-7087796-B1 | Cyclopropanecarboxaldehydes and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2006-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062405-A1 | CYCLOPROPANECARBOXALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | C5, TRPA1, CYP1B1 | TRPA1 2/4885CD81 4025/4885ATM 3312/4885 |
| US-20080026979-A1 | Cyclopropancarboxaldehydes and their use in perfume compositions | FAAH2, C5, TRPA1 | TRPA1 3/4885CD81 3983/4885ATM 3243/4885 |
| US-20060287557-A1 | CYCLOPROPANECARBOXALDEHYDES AND THEIR USE IN PERFUME COMPOSITIONS | C5, TRPA1, FAAH2 | TRPA1 2/4885CD81 4212/4885ATM 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.