Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL27749109 | 0.96 | HSD17B10 (0.48) | HSD17B10ALDH1A1HTTGAARAB9A | |
| Acetic Acid SCHEMBL28009360 | 0.91 | TSHR (0.47) | HSD17B10ALDH1A1HTTGAARAB9A | |
| SCHEMBL171809 | 0.83 | HSD17B10 (0.52) | HSD17B10ALDH1A1HTTGAARAB9A | |
| Ethoxycarbonyl Group SCHEMBL28254512 | 0.83 | HTT (0.39) | HSD17B10ALDH1A1HTTGAARAB9A | |
| Ammonia Solution, Strong SCHEMBL27551880 | 0.82 | HSD17B10 (0.50) | HSD17B10ALDH1A1HTTGAARAB9A | |
| SCHEMBL8568179 | 0.80 | ALDH1A1 (0.53) | ALDH1A1HTTGAARAB9ATSHR | |
| SCHEMBL27613328 | 0.77 | HSD17B10 (0.46) | HSD17B10ALDH1A1HTTGAARAB9A | |
| SCHEMBL4436893 | 0.77 | HSD17B10 (0.50) | HSD17B10ALDH1A1HTTGAATSHR | |
| Ethylene SCHEMBL27749127 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HTTGAARAB9ATSHR | |
| SCHEMBL12343951 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTGAARAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113980018-A | Preparation method of 6-azaindole | 苏州艾缇克药物化学有限公司 | 2022-01-28 | — | — | CN | claimed |
| CN-108822135-B | Synthesis method of nitrogen heterocyclic ring substituted thieno [3, 2-d ] thiazole and derivatives thereof | 湘潭大学 | 2021-02-02 | — | — | CN | claimed |
| CN-110015988-B | Preparation method of 3-amino-4-methylpyridine | 新发药业有限公司 | 2020-06-23 | — | — | CN | claimed |
| CN-110746348-A | Preparation method of 4-methyl-3-bromopyridine | 常州传侑环保科技有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-110015988-A | A kind of simple and convenient process for preparing of low cost 3- amino-4-methylpyridine | 新发药业有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-109761891-A | A kind of preparation method of 4- methyl -3- bromopyridine | 丹阳市宁大卫防检测技术有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-109201010-A | A kind of preparation method of the adsorbent material based on modified konjac glucomannan | 陕西镇安华兴特色农产品开发有限公司 | 2019-01-15 | — | — | CN | claimed |
| CN-106187870-A | A kind of 4 picoline location nitrations are the method for 3 nitro 4 picolines | 南京红太阳生物化学有限责任公司 | 2016-12-07 | — | — | CN | claimed |
| CN-103608393-B | The mono bath autodeposition coatings of metal base and preparation and application thereof for combination | 汉高股份有限及两合公司 | 2016-08-17 | — | — | CN | claimed |
| CN-104945314-A | Method for preparing 3-bromo-4-methylpyridine | HONG SHUAIJIN | 2015-09-30 | — | — | CN | claimed |
| CN-102161711-A | Method for preparing absorbing material based on modified konjac glucomannan | UNIV SW SCI & TECH SWUST | 2011-08-24 | — | — | CN | claimed |
| JP-4691506-B2 | — | — | 2011-06-01 | — | — | JP | claimed |
| US-7626027-B2 | Substituted 1H-pyrrolo[2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase Iε | AVENTIS PHARMACEUTICALS INC (US) | 2009-12-01 | — | — | US | claimed |
| EP-1747220-B1 | SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMA INC (US) | 2009-04-15 | — | — | EP | claimed |
| CN-100439367-C | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | AVENTIS PHARMA INC (US) | 2008-12-03 | — | — | CN | claimed |
| US-20080200496-A1 | SUBSTITUTED 1H-PYRROLO[3,2-b, 3,2-c, and 2,3-c]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Ie | AVENTIS PHARMACEUTICALS INC. (US) | 2008-08-21 | — | — | US | claimed |
| EP-1747220-A1 | SUBSTITUTED 1H-PYRROLO 3,2-B, 3,2-C, AND 2,3-C¨PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | Aventis Pharmaceuticals Inc. (US) | 2007-01-31 | — | — | EP | claimed |
| CN-1906194-A | Substituted 1H-pyrrolo [3, 2-b, 3, 2-c and 2, 3-c ] pyridine-2-carboxamides and related analogs as inhibitors of casein kinase ie | AVENTIS PHARMA INC (US) | 2007-01-31 | — | — | CN | claimed |
| WO-2005061498-A1 | SUBSTITUTED 1H-PYRROLO[3,2-B, 3,2-C, AND 2,3-C]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE I EPSILON | AVENTIS PHARMACEUTICALS INC. (US) | 2005-07-07 | — | — | WO | claimed |
| US-20050131012-A1 | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | AVENTIS PHARMACEUTICALS INC. (US) | 2005-06-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200496-A1 | SUBSTITUTED 1H-PYRROLO[3,2-b, 3,2-c, and 2,3-c]PYRIDINE-2-CARBOXAMIDES AND RELATED ANALOGS AS INHIBITORS OF CASEIN KINASE Ie | CSNK1E, CSNK1G3, CSNK2A3 | HSD17B10 3528/4885ALDH1A1 3613/4885HTT 3995/4885 |
| US-20050131012-A1 | Substituted 1H-pyrrolo[3,2-b, 3,2-c, and 2,3-c]pyridine-2-carboxamides and related analogs as inhibitors of casein kinase lepsilon | CSNK2A3, PACSIN2, CSNK1G3 | HSD17B10 2865/4885ALDH1A1 4044/4885HTT 3317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.