SCHEMBL815576

SCHEMBL815576

CCCCCCCCC=CCCCCCCCC(=O)c1cccs1

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.61
HDAC1 Q13547 2/20 0.57
MEN1 O00255 1/20 0.56
NPC1 O15118 1/20 0.56
ALDH1A1 P00352 1/20 0.56
LMNA P02545 1/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
KMT2A Q03164 1/20 0.56
FAAH O00519 6/20 0.53
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
SOAT2 O75908 1/20 0.50
SOAT1 P35610 1/20 0.50
CES1 P23141 3/20 0.49
DAGLA Q9Y4D2 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23859828 0.91 HPGD (0.73) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL3183371 0.91 HPGD (0.73) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL8972518 0.91 HPGD (0.73) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL9046710 0.91 HPGD (0.73) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL2787821 0.91 HPGD (0.73) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL3192172 0.89 HPGD (0.70) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL3177576 0.78 LMNA (0.77) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL22721189 0.78 ALDH1A1 (0.83) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL3383085 0.77 HPGD (1.00) HPGDHDAC1MEN1NPC1ALDH1A1
SCHEMBL3967018 0.76 MAPT (0.65) HDAC1LMNAPOLBKMT2AFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321363-B1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS MATERIA INC (US) 2020-04-22 EP disclosed
EP-2046719-B1 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE ELEVANCE RENEWABLE SCIENCES (US) 2013-09-04 EP disclosed
US-8324334-B2 Telechelic olefin metathesis polymers from renewable feedstocks MATERIA, INC. (US) 2012-12-04 US disclosed
US-8067623-B2 Producing waxes from soybean oil; ruthenium alkylidene catalytic, simultaneous opening and inserting ELEVANCE RENEWABLE SCIENCES, INC. (US) 2011-11-29 US disclosed
EP-2321363-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS Materia, Inc. (US) 2011-05-18 EP disclosed
WO-2010021740-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS MATERIA, INC. (US) 2010-02-25 WO disclosed
EP-2046719-A2 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE Elevance Renewable Sciences, Inc. (US) 2009-04-15 EP disclosed
US-20080064891-A1 Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like WILMAR TRADING PTE LTD (SG) 2008-03-13 US disclosed
WO-2008008440-A2 RING OPENING CROSS-METATHESIS REACTION OF CYCLIC OLEFINS WITH SEED OILS AND THE LIKE ELEVANCE RENEWABLE SCIENCES, INC. (US) 2008-01-17 WO disclosed
US-4873351-A REACTING ANTIMONY TRIOXIDE WITH ORGANIC MERCAPTAN IN THE PRESENCE OF A LOWER ALIPHATIC CARBOXYLIC ACID SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064891-A1 Ring opening cross-metathesis reaction of cyclic olefins with seed oils and the like SQLE, COASY, ALOX12 HPGD 1300/4885HDAC1 4744/4885MEN1 3380/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.