Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | PPARD | Q03181 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.54 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31946 | 0.81 | PPARG (0.58) | MAPTPPARGPPARDPPARACYP3A4 | |
| SCHEMBL31861 | 0.80 | PPARD (0.64) | PPARGPPARDPPARAPTGER4PTGER2 | |
| SCHEMBL9049946 | 0.77 | NFE2L2 (0.55) | MAPTCYP3A4ERN1 | |
| SCHEMBL12636541 | 0.76 | LIPG (0.52) | MAPTPPARGPPARDPPARACYP3A4 | |
| SCHEMBL184222 | 0.75 | MAPK14 (0.58) | MAPTPPARGPPARDPPARACYP3A4 | |
| SCHEMBL25688773 | 0.74 | CYP1A2 (0.53) | MAPTCYP3A4ERN1L3MBTL1 | |
| SCHEMBL4451065 | 0.73 | PTGER4 (0.79) | MAPTPPARGPPARDPPARACYP3A4 | |
| SCHEMBL5334043 | 0.73 | CYP1A2 (0.65) | PPARDPPARACYP3A4NR1H4L3MBTL1 | |
| SCHEMBL3031645 | 0.73 | MAPT (0.58) | MAPTPPARGCYP3A4MAPK14NR1H4 | |
| SCHEMBL17512413 | 0.72 | KMT2A (0.60) | MAPTPPARGPPARDPPARANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |