Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1379532 | 0.88 | TDP1 (0.61) | TDP1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL57166 | 0.87 | TDP1 (1.00) | TDP1ALDH1A1POLBCTSBNCOA1 | |
| SCHEMBL29475175 | 0.87 | TDP1 (1.00) | TDP1ALDH1A1POLBCTSBNCOA1 | |
| SCHEMBL28093598 | 0.84 | TDP1 (0.95) | TDP1ALDH1A1KMT2AMEN1POLB | |
| Methyl Alcohol SCHEMBL28304524 | 0.80 | TDP1 (0.86) | TDP1ALDH1A1POLBCTSBNCOA1 | |
| SCHEMBL5071420 | 0.80 | TDP1 (0.57) | TDP1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9078242 | 0.80 | TDP1 (0.57) | TDP1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11722245 | 0.80 | TDP1 (0.62) | TDP1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL4871313 | 0.79 | TDP1 (0.61) | TDP1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL25561358 | 0.79 | S100A4 (0.56) | TDP1ALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410256-C | Optical diamine monomer containing di-dehydrated-hexitol unit and process for preparing same | UNIV TSINGHUA (CN) | 2008-08-13 | — | — | CN | claimed |
| CN-1320031-C | Polyamide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2007-06-06 | — | — | CN | claimed |
| CN-1702071-A | Optical diamine monomer containing di-dehydrated-hexitol unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1702097-A | Optical polyimide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1702095-A | Polyamide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-11-09 | — | — | US | disclosed |
| US-20230242544-A1 | QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-08-03 | — | — | US | disclosed |
| CN-113754598-B | Diamine and polyimide containing cyclic peptide structure and preparation method thereof | 四川大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113754598-A | Diamine containing cyclopeptide structure, polyimide and preparation method thereof | 四川大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-106432240-B | The polyimides and preparation method thereof of aromatic diamine of the structure containing adenine and preparation method thereof and the structure containing adenine | 四川大学 | 2018-11-09 | — | — | CN | disclosed |
| CN-106432240-A | Aromatic diamine containing adenine structure, preparation method of aromatic diamine, polyimide containing adenine structure and preparation method of polyimide | 四川大学 | 2017-02-22 | — | — | CN | disclosed |
| US-7655689-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-20040077605-A1 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY | 2004-04-22 | — | — | US | disclosed |
| WO-2003062241-A1 | FUSED HETEROCYCLIC SUCCINIMIDECOMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-31 | — | — | WO | disclosed |
| EP-1319007-A1 | FUSED HETEROCYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | Bristol-Myers Squibb Company (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024702-A1 | FUSED HETEROCYCLIC SUCCINIMIDE COMPOUNDS AND ANALOGS THEREOF, MODULATORS OF NUCLEAR HORMONE RECEPTOR FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |
| US-5453495-A | Disazo compounds containing an optionally substituted piperazinyl group | ZENECA LIMITED (GB) | 1995-09-26 | — | — | US | disclosed |
| WO-1995017471-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| WO-1995017472-A1 | DISAZO COMPOUND | ZENECA LIMITED (GB) | 1995-06-29 | — | — | WO | disclosed |
| CN-87102669-A | Fiberboard and manufacture method thereof | — | 1987-12-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077605-A1 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | NCOA1, NCOA3, NR5A2 | TDP1 4323/4885ALDH1A1 3219/4885KMT2A 1432/4885 |
| US-20230242544-A1 | QUINAZOLINE COMPOUNDS, PREPARATION METHODS AND USES THEREOF | KRAS, NRAS, HRAS | TDP1 2833/4885ALDH1A1 1817/4885KMT2A 1113/4885 |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | KRAS, NRAS, HRAS | TDP1 4075/4885ALDH1A1 1158/4885KMT2A 1189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.