Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193192 | 0.88 | TDP1 (0.75) | TDP1CTSBALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL7788656 | 0.87 | TDP1 (0.80) | TDP1CTSBALDH1A1KDM4EMEN1 | |
| SCHEMBL18810941 | 0.81 | ALDH1A1 (0.52) | TDP1ALDH1A1CYP1A2CYP2A6KDM4E | |
| SCHEMBL9078242 | 0.80 | TDP1 (0.57) | TDP1CTSBALDH1A1KDM4EMEN1 | |
| SCHEMBL4871313 | 0.79 | TDP1 (0.61) | TDP1CTSBALDH1A1KDM4EMEN1 | |
| SCHEMBL57166 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1TSHRGAA | |
| SCHEMBL29475175 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1TSHRGAA | |
| SCHEMBL15302617 | 0.76 | TDP1 (0.50) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5071420 | 0.76 | TDP1 (0.57) | TDP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL619318 | 0.76 | MAPT (0.52) | TDP1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025043967-A1 | PREPARATION METHOD FOR AND USE OF NANOPOROUS CARBON MATERIAL HAVING CONTINUOUS STRUCTURE | 东南大学 | 2025-03-06 | — | — | WO | claimed |
| CN-118515261-A | Preparation method of nano porous carbon material with continuous structure and application of nano porous carbon material as heat insulation material | 东南大学 | 2024-08-20 | — | — | CN | claimed |
| CN-117088357-A | Preparation method and application of nano porous carbon material with continuous structure | 东南大学 | 2023-11-21 | — | — | CN | claimed |
| CN-116925498-A | High-pressure-bearing branched epoxy resin plugging material and oil-based drilling fluid | 西南石油大学 | 2023-10-24 | — | — | CN | claimed |
| JP-4731114-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| US-20100222330-A1 | New Compounds | BIOVITRUM AB (SE) | 2010-09-02 | — | — | US | claimed |
| US-7572787-B2 | Substituted naphthalene sulfonamides | BIOVITRUM AB (SE) | 2009-08-11 | — | — | US | claimed |
| CN-100410256-C | Optical diamine monomer containing di-dehydrated-hexitol unit and process for preparing same | UNIV TSINGHUA (CN) | 2008-08-13 | — | — | CN | claimed |
| CN-1320031-C | Polyamide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2007-06-06 | — | — | CN | claimed |
| US-20070066598-A1 | Compounds | BIOVITRUM AB, A SWEDEN CORPORATION | 2007-03-22 | — | — | US | claimed |
| US-20070066600-A1 | Compounds | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2007-03-22 | — | — | US | claimed |
| CN-1800185-A | Substituted sulfonamide compounds, process for their use as medicament for the treatment of CNS disorders, obesity and type II diabetes. | BIOVITRUM AB (SE) | 2006-07-12 | — | — | CN | claimed |
| CN-1702097-A | Optical polyimide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1702095-A | Polyamide containing isosorbide unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1702071-A | Optical diamine monomer containing di-dehydrated-hexitol unit and process for preparing same | UNIV TSINGHUA (CN) | 2005-11-30 | — | — | CN | claimed |
| CN-1522245-A | Substituted sulfonamide compounds, process for their preparation and their use as medicaments for the treatment of CNS disorders, obesity and type II diabetes | �Ȱ�ά����ķ�ɷݹ�˾ | 2004-08-18 | — | — | CN | claimed |
| EP-1412325-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2004-04-28 | — | — | EP | claimed |
| US-20030158202-A1 | Substituted fused ring sulfonamides containing, e.g., naphthalene, isoquinoline, quinoline, benzofuran or benzothiophene rings; treatment of conditions relating to obesity, type II diabetes and CNS disorders | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2003-08-21 | — | — | US | claimed |
| WO-2002100822-A1 | SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES | BIOVITRUM AB (SE) | 2002-12-19 | — | — | WO | claimed |
| US-4375550-A | Hydrogenation of halogen-substituted aromatic nitro compounds | JOHNSON, MATTHEY & CO., LIMITED (GB) | 1983-03-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066598-A1 | Compounds | SULT2A1, STS, SLC5A2 | TDP1 4117/4885CTSB 1626/4885ALDH1A1 262/4885 |
| US-20030158202-A1 | Substituted fused ring sulfonamides containing, e.g., naphthalene, isoquinoline, quinoline, benzofuran or benzothiophene rings; treatment of conditions relating to obesity, type II diabetes and CNS disorders | SULT2A1, SULT1A1, SULT1E1 | TDP1 2654/4885CTSB 3013/4885ALDH1A1 401/4885 |
| US-20070066600-A1 | Compounds | SULT2A1, STS, SLC5A2 | TDP1 4117/4885CTSB 1626/4885ALDH1A1 262/4885 |
| US-20100222330-A1 | New Compounds | SULT2A1, GPR119, STS | TDP1 4016/4885CTSB 1810/4885ALDH1A1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.