SCHEMBL3193296

SCHEMBL3193296

ClC(Cl)=CCOc1cc(Cl)c(OCCBr)c(Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
PLAU P00749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2349043 0.92 HTT (0.35) HTTPLAU
SCHEMBL3238838 0.91 PLAU (0.35) HTTPLAU
SCHEMBL4045927 0.90 KLK1 (0.35) HTTPLAU
SCHEMBL8408794 0.89 HTT (0.39) HTTPLAU
SCHEMBL8408754 0.89 HTT (0.39) HTTPLAU
SCHEMBL8407690 0.87 HTT (0.41) HTTPLAU
SCHEMBL2444928 0.86 HTT (0.37) HTTPLAU
SCHEMBL3138415 0.86 HTT (0.37) HTTPLAU
SCHEMBL7632172 0.84 HTT (0.36) HTTPLAU
SCHEMBL8666882 0.84 HTT (0.36) HTTPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671201-B2 Phenyl substituted cyclic derivatives FMC CORPORATION (US) 2010-03-02 US disclosed
US-7671201-B2 Phenyl substituted cyclic derivatives FMC CORPORATION (US) 2010-03-02 US disclosed
US-7671201-B2 Phenyl substituted cyclic derivatives FMC CORPORATION (US) 2010-03-02 US disclosed
EP-1620401-A4 PHENYL SUBSTITUTED CYCLIC DERIVATIVES BAYER CROPSCIENCE AG (DE) 2008-08-13 EP disclosed
US-20060270726-A1 Phenyl substituted cyclic derivatives FMC CORPORATION 2006-11-30 US disclosed
EP-1620401-A2 PHENYL SUBSTITUTED CYCLIC DERIVATIVES FMC CORPORATION (US) 2006-02-01 EP disclosed
WO-2004099145-A2 PHENYL SUBSTITUTED CYCLIC DERIVATIVES FMC CORPORATION (US) 2004-11-18 WO disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060270726-A1 Phenyl substituted cyclic derivatives DDT, L3MBTL4, L3MBTL3 HTT 4802/4885PLAU 4792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.