Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BCL3 | P20749 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31954 | 0.89 | PPARA (0.54) | PPARGPPARDPPARACNR2LMNA | |
| SCHEMBL31949 | 0.88 | PPARA (0.55) | PPARGPPARDPPARACNR2LMNA | |
| SCHEMBL31889 | 0.84 | PPARA (0.51) | PPARGPPARDPPARALMNALIPG | |
| SCHEMBL31880 | 0.81 | PPARD (0.54) | PPARGPPARDPPARACNR2LMNA | |
| SCHEMBL31948 | 0.80 | PPARA (0.58) | PPARGPPARDPPARACNR2LMNA | |
| SCHEMBL12636184 | 0.77 | PPARA (0.59) | PPARGPPARDPPARACNR2LMNA | |
| SCHEMBL12636546 | 0.77 | PPARA (0.61) | PPARGPPARDPPARACNR2LMNA | |
| SCHEMBL31780 | 0.75 | PPARD (0.53) | PPARGPPARDPPARACNR2LIPG | |
| SCHEMBL12634669 | 0.75 | PPARA (0.61) | PPARGPPARDPPARALMNALIPG | |
| SCHEMBL12634655 | 0.74 | PPARA (0.58) | PPARGPPARDPPARACNR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026495-A1 | NOVEL HYDANTOIN DERIVATIVE AND MEDICINAL AGENT COMPRISING SAME AS ACTIVE INGREDIENT | 杏林製薬株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |