Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194460 | 1.00 | ALDH1A1 (0.39) | ALDH1A1MAPTFTOIDEHPGD | |
| SCHEMBL3197451 | 0.90 | GSTA1 (0.40) | ALDH1A1MAPTIDEHPGDKMT2A | |
| SCHEMBL3197447 | 0.90 | GSTA1 (0.40) | ALDH1A1MAPTIDEHPGDKMT2A | |
| SCHEMBL3192196 | 0.85 | PPARG (0.41) | ALDH1A1MAPTFTOIDEHPGD | |
| SCHEMBL3192190 | 0.85 | PPARG (0.41) | ALDH1A1MAPTFTOIDEHPGD | |
| SCHEMBL3185002 | 0.78 | NPC1 (0.45) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL3185014 | 0.78 | NPC1 (0.45) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A | |
| SCHEMBL3188163 | 0.77 | PPARG (0.39) | MAPTIDEHPGDKMT2AMEN1 | |
| SCHEMBL3188158 | 0.77 | PPARG (0.39) | MAPTIDEHPGDKMT2AMEN1 | |
| SCHEMBL16693333 | 0.75 | MAPT (0.54) | ALDH1A1MAPTHPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1867683-B1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO LTD (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-7662937-B2 | Polymerizable dye and ophthalmic lens containing the same | MENICON CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090082553-A1 | Novel Polymerizable Dye and Ophthalmic Lens Containing the Same | MENICON CO., LTD. (JP) | 2009-03-26 | — | — | US | disclosed |
| EP-1867683-A1 | NOVEL POLYMERIZABLE DYE AND OPHTHALMIC LENS CONTAINING THE SAME | MENICON CO., LTD. (JP) | 2007-12-19 | — | — | EP | disclosed |