Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5959576 | 0.84 | KDM4E (0.46) | ALDH1A1SMN1; SMN2NPSR1KDM4ECYP2C19 | |
| SCHEMBL2942871 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL2130243 | 0.82 | EGFR (0.47) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL9189177 | 0.82 | ESR1 (0.47) | ALDH1A1SMN1; SMN2NPSR1KDM4EMAPT | |
| SCHEMBL5861632 | 0.82 | ESR1 (0.47) | ALDH1A1SMN1; SMN2NPSR1KDM4EMAPT | |
| SCHEMBL11436470 | 0.81 | KDM4E (0.62) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL12213687 | 0.80 | ESR1 (0.52) | ALDH1A1SMN1; SMN2HTTNPSR1HSD17B10 | |
| SCHEMBL6671333 | 0.79 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 | |
| SCHEMBL12213691 | 0.78 | CYP2C19 (0.68) | ALDH1A1SMN1; SMN2HTTNPSR1CYP2C19 | |
| SCHEMBL12024903 | 0.78 | KDM4E (0.56) | ALDH1A1SMN1; SMN2POLBHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6551360-B2 | Pyrazoline-3,5-dione-containing compositions for dyeing keratin fibres; their use in dyeing as couplers; dyeing process | VIDAL LAURENT (FR) | 2003-04-22 | — | — | US | claimed |
| US-6340372-B1 | Compositions for dyeing keratin fibers containing S-oxide-thiazolo-azoles and/or S,S-dioxide-thiazolo-azoles; their use for dyeing as couplers, method of dyeing | L'OREAL S.A. (FR) | 2002-01-22 | — | — | US | claimed |
| US-6139589-A | HAIR DYES | L'OREAL S.A. (FR) | 2000-10-31 | — | — | US | claimed |
| US-6063136-A | Compositions containing pyrrolo-oxazole couplers for dyeing keratin fibers and dyeing methods | L'OREAL S.A. (FR) | 2000-05-16 | — | — | US | claimed |
| US-11142498-B2 | Keratin dyeing compounds, compositions containing them, and method and use thereof | WELLA OPERATIONS US, LLC (US) | 2021-10-12 | — | — | US | disclosed |
| US-20200247749-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | WELLA OPERATIONS US, LLC | 2020-08-06 | — | — | US | disclosed |
| WO-2019074736-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | NOXELL CORPORATION (US) | 2019-04-18 | — | — | WO | disclosed |
| US-7678158-B2 | Compositions for oxidatively dyeing keratin fibers and methods for using such compositions | THE PROCTER & GAMBLE COMPANY (US) | 2010-03-16 | — | — | US | disclosed |
| EP-1720615-B1 | COSMETIC HAIR DYEING COMPOSITIONS CONTAINING THEM AND USE THEREOF | PROCTER & GAMBLE (US) | 2009-12-30 | — | — | EP | disclosed |
| US-20090144914-A1 | COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS | LIM MU LLL | 2009-06-11 | — | — | US | disclosed |
| US-7507262-B2 | Compositions for oxidatively dyeing keratin fibers and methods for using such compositions | THE PROCTER & GAMBLE COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-7491245-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2009-02-17 | — | — | US | disclosed |
| EP-0200206-A2 | Silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1986-11-05 | — | — | EP | disclosed |
| EP-0199351-A2 | Silver halide photographic material | KONICA CORPORATION (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0199604-A2 | Processing method for light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0187521-A2 | Light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1986-07-16 | — | — | EP | disclosed |
| EP-0185506-A2 | Light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1986-06-25 | — | — | EP | disclosed |
| EP-0182486-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-05-28 | — | — | EP | disclosed |
| EP-0178794-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0178165-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090144914-A1 | COMPOSITIONS FOR OXIDATIVELY DYEING KERATIN FIBERS AND METHODS FOR USING SUCH COMPOSITIONS | KRT18, AKR7A2, AKR1C4 | ALDH1A1 205/4885SMN1; SMN2 4524/4885POLB 219/4885 |
| US-11142498-B2 | Keratin dyeing compounds, compositions containing them, and method and use thereof | KRT18, MARK4, MKI67 | ALDH1A1 334/4885SMN1; SMN2 4882/4885POLB 1062/4885 |
| US-20200247749-A1 | KERATIN DYEING COMPOUNDS, COMPOSITIONS CONTAINING THEM, AND METHOD AND USE THEREOF | KRT18, PRKDC, MKI67 | ALDH1A1 385/4885SMN1; SMN2 4883/4885POLB 1067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.