Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 14/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3209995 | 0.82 | LMNA (0.42) | — | |
| SCHEMBL1858647 | 0.77 | GPR52 (0.46) | GPR52 | |
| SCHEMBL13506352 | 0.76 | GPR52 (0.53) | GPR52ADORA2ALTA4H | |
| SCHEMBL1849577 | 0.76 | GPR52 (0.51) | GPR52ADORA2ALTA4H | |
| SCHEMBL1849991 | 0.76 | CYP2A6 (0.41) | — | |
| SCHEMBL3215860 | 0.73 | GPR52 (0.45) | GPR52HTR2AHTR2CHTR2B | |
| SCHEMBL13505746 | 0.73 | GPR52 (0.48) | GPR52ADORA2ALTA4H | |
| SCHEMBL13506123 | 0.72 | GPR52 (0.55) | GPR52ABL1 | |
| SCHEMBL1855573 | 0.72 | GPR52 (0.48) | GPR52HTR2AHTR2CHTR2B | |
| SCHEMBL13505792 | 0.71 | GPR52 (0.58) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2518054-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | GPR52 1/4885ABL1 2539/4885HTR2A 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.