Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663065 | 0.89 | ESR2 (0.40) | TSHRESR2CXCR1CXCR2AR | |
| SCHEMBL1233144 | 0.81 | TSHR (0.60) | TSHRARALDH1A1KDM4ELMNA | |
| SCHEMBL28637531 | 0.74 | TSHR (0.52) | TSHRTRPA1ATMESR2LDHA | |
| O-Xylene SCHEMBL7156378 | 0.74 | TSHR (0.76) | TSHRESR2ACHEARALDH1A1 | |
| O-Xylene SCHEMBL28253952 | 0.74 | TSHR (0.95) | TSHRESR2ACHEARALDH1A1 | |
| SCHEMBL29458226 | 0.74 | — | — | |
| SCHEMBL2046791 | 0.74 | — | — | |
| SCHEMBL30755480 | 0.74 | TSHR (0.52) | TSHRTRPA1ATMESR2AR | |
| SCHEMBL27373681 | 0.74 | TSHR (0.52) | TSHRTRPA1ATMESR2AR | |
| SCHEMBL832 | 0.73 | TSHR (0.46) | TSHRESR2CXCR1CXCR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11028115-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11028116-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-06-08 | — | — | US | disclosed |
| US-11008359-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-18 | — | — | US | disclosed |
| US-10995111-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-05-04 | — | — | US | disclosed |
| US-20210047357-A1 | LABELLED NUCLEOTIDES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2021-02-18 | — | — | US | disclosed |
| US-20210009623-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2021-01-14 | — | — | US | disclosed |
| US-20210009622-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2021-01-14 | — | — | US | disclosed |
| US-20200325167-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2020-10-15 | — | — | US | disclosed |
| US-20200087336-A1 | LABELLED NUCLEOTIDES | SOLEXA LIMITED (GB) | 2020-03-19 | — | — | US | disclosed |
| US-10487102-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2019-11-26 | — | — | US | disclosed |
| US-7795424-B2 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-09-14 | — | — | US | disclosed |
| US-20090062145-A1 | Labelled nucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-7414116-B2 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2008-08-19 | — | — | US | disclosed |
| US-20060275843-A1 | Methods for diagnosing the presence or stage of cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-12-07 | — | — | US | disclosed |
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | ILLUMINA CAMBRIDGE LIMITED (GB) | 2006-07-20 | — | — | US | disclosed |
| US-5879950-A | ADDITION OF PHOSPHATIDYL CHOLINES (LECITHINS) TO CELL-FREE REACTION MIXTURE INCREASES RESTRICTION ENZYME RATE | HELSINKI UNIVERSITY LICENSING LTD. OY (FI) | 1999-03-09 | — | — | US | disclosed |
| US-5830643-A | DETECTING A TARGET NUCLEIC ACID | CANON KABUSHIKI KAISHA (JP) | 1998-11-03 | — | — | US | disclosed |
| WO-1996040899-A1 | MATERIALS AND METHODS FOR DIGESTING DNA OR RNA USING RESTRICTION ENDONUCLEASES | HELSINKI UNIVERSITY LICENSING LTD. OY (FI) | 1996-12-19 | — | — | WO | disclosed |
| EP-0385410-B1 | Partially double-stranded oligonucleotide and method for forming oligonucleotide | CANON KK (JP) | 1996-10-02 | — | — | EP | disclosed |
| EP-0385410-A2 | Partially double-stranded oligonucleotide and method for forming oligonucleotide | CANON KABUSHIKI KAISHA (JP) | 1990-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200325167-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-20060160081-A1 | certain linkers connecting nucleotide bases to detachable labels (fluorophores) are cleaved using water soluble phosphines transition metal catalysts; sequencing; used in nick translation, random primer labeling, end-labeling (terminal deoxynucleotidyltransferase), reverse transcription, amplification | RNGTT, DNTT, POLQ | TSHR 2634/4885TRPA1 3982/4885ATM 3867/4885 |
| US-20210009623-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-20210009622-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-11008359-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-20210047357-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-10995111-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-20200087336-A1 | LABELLED NUCLEOTIDES | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-11028116-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-11028115-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TSHR 3330/4885TRPA1 4645/4885ATM 3879/4885 |
| US-10487102-B2 | Labelled nucleotides | NUDT1, DUT, NT5C2 | TSHR 3376/4885TRPA1 4623/4885ATM 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.