SCHEMBL319633

SCHEMBL319633

CC1=Cc2ccccc2C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 2/20 0.46
MAOB P27338 2/20 0.44
MAOA P21397 1/20 0.44
ACHE P22303 2/20 0.42
CYP11B2 P19099 2/20 0.41
CYP11B1 P15538 1/20 0.41
TRPA1 O75762 1/20 0.40
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
GPR84 Q9NQS5 1/20 0.37
DRD2 P14416 2/20 0.37
DRD4 P21917 2/20 0.37
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.36
ALOX12 P18054 1/20 0.36
CYP1A2 P05177 1/20 0.36
HTR1A P08908 1/20 0.36
HTR2A P28223 1/20 0.36
HTR7 P34969 1/20 0.36
DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370486 1.00 PTGS2 (0.46) PTGS2MAOBMAOAACHECYP11B2
SCHEMBL8737400 0.97 PTGS2 (0.44) PTGS2MAOBMAOAACHECYP11B2
Bromide SCHEMBL31108155 0.97 PTGS2 (0.44) PTGS2MAOBMAOAACHECYP11B2
Lithium SCHEMBL29594699 0.97 PTGS2 (0.44) PTGS2MAOBMAOAACHECYP11B2
Hydrochloric Acid SCHEMBL8319749 0.95 PTGS2 (0.43) PTGS2MAOBMAOAACHECYP11B2
Hydrochloric Acid SCHEMBL8030722 0.95 CYP11B2 (0.43) PTGS2MAOBMAOAACHECYP11B2
Hydrochloric Acid SCHEMBL7076887 0.95 CYP11B2 (0.43) PTGS2MAOBMAOAACHECYP11B2
SCHEMBL7082648 0.81 PTGS2 (0.38) PTGS2MAOBMAOAACHECYP11B2
SCHEMBL29594499 0.80 KDM1A (0.46) PTGS2MAOBCYP11B2CYP11B1GPR84
SCHEMBL5029738 0.80 KDM1A (0.46) PTGS2MAOBCYP11B2CYP11B1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1057 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
US-11498985-B2 Continuous synthesis of an ethylene and butadiene copolymer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-11-15 US claimed
US-20220135717-A1 CONTINUOUS SYNTHESIS OF AN ETHYLENE AND BUTADIENE COPOLYMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2022-05-05 US claimed
CN-113754803-A Catalyst system and application thereof as catalyst for olefin polymerization 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-113754801-A Solid catalyst for preparing olefin polymer and solid catalyst system 中国石油化工股份有限公司 2021-12-07 CN claimed
CN-113754802-A Catalyst system for olefin polymerization reaction and prepolymerization catalyst composition 中国石油化工股份有限公司 2021-12-07 CN claimed
US-11136422-B2 Continuous synthesis of an ethylene and butadiene copolymer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-10-05 US claimed
EP-3390465-B1 ETHYLENE/BUTADIENE COPOLYMER OF HOMOGENEOUS MICROSTRUCTURE MICHELIN & CIE (FR) 2021-05-19 EP claimed
CN-109071685-B Terminal-modified conjugated diene polymer, rubber composition, and rubber article 株式会社普利司通 2020-12-01 CN claimed
US-20200131288-A1 CONTINUOUS SYNTHESIS OF AN ETHYLENE AND BUTADIENE COPOLYMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-04-30 US claimed
US-6316567-B1 DURABILITY OF TIRE TREADS THE GOODYEAR TIRE & RUBBER COMPANY 2001-11-13 US claimed
US-6265478-B1 PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY 2001-07-24 US claimed
US-6262197-B1 AS POLYMERIZATION CATALYST IN OLEFIN POLYMERIZATION TARGOR GMBH (DE) 2001-07-17 US claimed
US-6228944-B1 PNEUMATIC TIRE TREAD HAVING GREATER TRACTION AND WEAR RESISTANCE THE GOODYEAR TIRE & RUBBER COMPANY 2001-05-08 US claimed
EP-1077223-A1 Polymeric resinous material derived from limonene, dicyclopentadiene, indene and alpha-methyl styrene THE GOODYEAR TIRE & RUBBER COMPANY (US) 2001-02-21 EP claimed
EP-1063246-A1 Polymeric resinous material derived from limonene, dimethyl-dicyclopentadiene, indene and vinyl toluene THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-12-27 EP claimed
EP-1029873-A1 Polymeric resinous material derived from limonene, dicylopentadiene, indene and vinyl toluene THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-08-23 EP claimed
CN-1253959-A Polymer resin material derived from limonene, bicyclopentadiene, indene and tert-butyl styrene GOODYEAR TIRE & RUBBER (US) 2000-05-24 CN claimed
EP-0990669-A1 Polymeric resinous material derived from limonene, dicyclopentadiene, indene and tertiarybutyl styrene THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-04-05 EP claimed
US-5670681-A Process for preparing a carbon-bridged biscyclopentadiene compound HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-23 US claimed