Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319633 | 1.00 | PTGS2 (0.46) | PTGS2MAOBMAOAACHECYP11B2 | |
| SCHEMBL8737400 | 0.97 | PTGS2 (0.44) | PTGS2MAOBMAOAACHECYP11B2 | |
| Bromide SCHEMBL31108155 | 0.97 | PTGS2 (0.44) | PTGS2MAOBMAOAACHECYP11B2 | |
| Lithium SCHEMBL29594699 | 0.97 | PTGS2 (0.44) | PTGS2MAOBMAOAACHECYP11B2 | |
| Hydrochloric Acid SCHEMBL8319749 | 0.95 | PTGS2 (0.43) | PTGS2MAOBMAOAACHECYP11B2 | |
| Hydrochloric Acid SCHEMBL8030722 | 0.95 | CYP11B2 (0.43) | PTGS2MAOBMAOAACHECYP11B2 | |
| Hydrochloric Acid SCHEMBL7076887 | 0.95 | CYP11B2 (0.43) | PTGS2MAOBMAOAACHECYP11B2 | |
| SCHEMBL7082648 | 0.81 | PTGS2 (0.38) | PTGS2MAOBMAOAACHECYP11B2 | |
| SCHEMBL29594499 | 0.80 | KDM1A (0.46) | PTGS2MAOBCYP11B2CYP11B1GPR84 | |
| SCHEMBL5029738 | 0.80 | KDM1A (0.46) | PTGS2MAOBCYP11B2CYP11B1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240343750-A1 | Metallocene Catalyst Compounds for Producing Polyolefins | EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) | 2024-10-17 | — | — | US | disclosed |
| US-11802170-B2 | Polyolefins prepared with binuclear metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2023-10-31 | — | — | US | disclosed |
| WO-2023191721-A2 | PRODUCTION OF ENANTIOPURE ALCOHOLS, AMINES AND ACIDS FROM ALKENES BY CASCADE BIOTRANSFORMATION INVOLVING 1,2-METHYL SHIFT | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-10-05 | — | — | WO | disclosed |
| US-20220372178-A1 | Polyolefins Prepared with Binuclear Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2022-11-24 | — | — | US | disclosed |
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-11-08 | — | — | US | disclosed |
| US-11339234-B2 | Propylene random copolymer | LG CHEM, LTD. | 2022-05-24 | — | — | US | disclosed |
| WO-2022070758-A1 | TRANSPARENT ARTICLE | ポリプラスチックス株式会社 | 2022-04-07 | — | — | WO | disclosed |
| WO-2022024549-A1 | METHOD FOR PRODUCING CYCLOOLEFIN COPOLYMER | ポリプラスチックス株式会社 | 2022-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11802170-B2 | Polyolefins prepared with binuclear metallocene catalysts | C1S, C9, C5 | PTGS2 3793/4885MAOB 1549/4885MAOA 2170/4885 |
| US-11492425-B2 | Metallocene catalyst compositions and polymerization process therewith | TERT, MDM4, PCBP1 | PTGS2 2131/4885MAOB 2412/4885MAOA 2063/4885 |
| US-20240343750-A1 | Metallocene Catalyst Compounds for Producing Polyolefins | MLX, TSNAX, TXLNA | PTGS2 1980/4885MAOB 1809/4885MAOA 296/4885 |
| US-11339234-B2 | Propylene random copolymer | PRUNE1, PIP5K1A, PIP5K1C | PTGS2 232/4885MAOB 4276/4885MAOA 4351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.