Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120812 | 0.88 | KMT2A (0.33) | MEN1MAPK1KMT2A | |
| SCHEMBL21624845 | 0.88 | KMT2A (0.33) | MEN1MAPK1KMT2A | |
| SCHEMBL3197007 | 0.86 | KMT2A (0.34) | MEN1MAPK1KMT2A | |
| SCHEMBL3197011 | 0.86 | KMT2A (0.34) | MEN1MAPK1KMT2A | |
| SCHEMBL15760564 | 0.83 | OPRM1 (0.37) | MEN1MAPK1KMT2A | |
| SCHEMBL1649897 | 0.80 | KMT2A (0.34) | MEN1MAPK1KMT2A | |
| SCHEMBL23120791 | 0.80 | KMT2A (0.38) | MEN1MAPK1KMT2ABTK | |
| SCHEMBL2340622 | 0.80 | KMT2A (0.38) | MEN1MAPK1KMT2ABTK | |
| SCHEMBL15645461 | 0.79 | KMT2A (0.47) | MEN1MAPK1KMT2A | |
| SCHEMBL29862721 | 0.79 | GAA (0.37) | MEN1MAPK1KMT2ABTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | YICHANG HUMANWELL PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | US | disclosed |
| WO-2021026492-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | Humanwell Pharmaceutical US (US) | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | OPRK1, OPRL1, OPRD1 | MEN1 4839/4885MAPK1 2818/4885KMT2A 1829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.