Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29745787 | 0.87 | ESR1 (0.34) | PTGS2ALDH1A1LMNATDP1ESR1 | |
| SCHEMBL3186451 | 0.86 | MAPT (0.42) | PTGS2MAPTPOLBPKMELANE | |
| Trifluoromethanesulfonic Acid SCHEMBL3421883 | 0.81 | MAPT (0.49) | PTGS2MAPTPOLBPKMELANE | |
| SCHEMBL29745873 | 0.80 | ENPP3 (0.33) | GAATDP1 | |
| SCHEMBL2436488 | 0.77 | LTA4H (0.45) | NPC1RAB9ATSHR | |
| SCHEMBL3104515 | 0.77 | TSHR (0.41) | PTGS2ALDH1A1GAALMNANPC1 | |
| SCHEMBL3126062 | 0.76 | TSHR (0.40) | PTGS2ALDH1A1GAALMNANPC1 | |
| SCHEMBL3130567 | 0.76 | TSHR (0.40) | PTGS2ALDH1A1GAALMNANPC1 | |
| SCHEMBL2439305 | 0.75 | TP53 (0.41) | TSHR | |
| SCHEMBL2434770 | 0.75 | LTA4H (0.45) | NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678528-B2 | Photoactive compounds | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-03-16 | — | — | US | claimed |
| EP-2384457-B1 | COATING COMPOSITIONS | MERCK PATENT GMBH (DE) | 2022-07-06 | — | — | EP | disclosed |