Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL22685960 | 0.97 | ALDH1A1 (0.43) | ALDH1A1HSD17B10MAPTSIGMAR1EPHX1 | |
| SCHEMBL6069315 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28366332 | 0.88 | — | — | |
| SCHEMBL7727423 | 0.76 | ADH1C (0.39) | ALDH1A1HSD17B10MAPTSIGMAR1EPHX1 | |
| SCHEMBL28140784 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HSD17B10MAPTSIGMAR1EPHX1 | |
| SCHEMBL24329483 | 0.76 | ADH1C (0.39) | ALDH1A1HSD17B10MAPTSIGMAR1EPHX1 | |
| SCHEMBL24083946 | 0.76 | ADH1C (0.39) | ALDH1A1HSD17B10MAPTSIGMAR1EPHX1 | |
| Trimethylammonium SCHEMBL28209024 | 0.73 | ALDH1A1 (0.75) | ALDH1A1HSD17B10MAPTSIGMAR1EPHX1 | |
| SCHEMBL28426716 | 0.72 | EPHX1 (0.41) | ALDH1A1MAPTEPHX1 | |
| SCHEMBL6993379 | 0.71 | EPHX1 (0.43) | ALDH1A1MAPTEPHX1CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 453 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025027093-A1 | CLOSED CELL POLYURETHANE FOAM SPRAY ADDITIVES FOR IMPROVING ADHESION UNDER LOW TEMPERATURE CONDITIONS | EVONIK OPERATIONS GMBH (DE) | 2025-02-06 | — | — | WO | claimed |
| WO-2024175628-A1 | INHIBITING SOLIDS FORMATION IN CO2 POLYURETHANE PRODUCTION | EVONIK OPERATIONS GMBH (DE) | 2024-08-29 | — | — | WO | claimed |
| US-10364315-B2 | Tertiary amine composition and method for making the composition | EVONIK DEGUSSA GMBH (DE) | 2019-07-30 | — | — | US | claimed |
| CN-106397730-B | The manufacturing method of tertiary amine composition and the composition | 赢创德固赛有限公司 | 2019-03-29 | — | — | CN | claimed |
| US-10119002-B2 | Additives for improving polyurethane foam performance | EVONIK DEGUSSA GMBH (DE) | 2018-11-06 | — | — | US | claimed |
| US-20180214857-A1 | N,N,N'-Trimethyl-Bis-(Aminoethyl) Ether and its Derivatives as Catalysts for Polyurethanes | EVONIK OPERATIONS GMBH (DE) | 2018-08-02 | — | — | US | claimed |
| US-9878317-B2 | N,N,N′-trimethyl-bis-(aminoethyl) ether and its derivatives as catalysts for polyurethanes | EVONIK DEGUSSA GMBH (DE) | 2018-01-30 | — | — | US | claimed |
| US-20170313805-A1 | TERTIARY AMINE COMPOSITION AND METHOD FOR MAKING THE COMPOSITION | EVONIK OPERATIONS GMBH (DE) | 2017-11-02 | — | — | US | claimed |
| US-9708436-B2 | Tertiary amine composition and method for making the composition | EVONIK DEGUSSA GMBH (DE) | 2017-07-18 | — | — | US | claimed |
| CN-106397730-A | Tertiary amine composition and method for making the composition | 气体产品与化学公司 | 2017-02-15 | — | — | CN | claimed |
| US-20160222153-A1 | TERTIARY AMINE COMPOSITION AND METHOD FOR MAKING THE COMPOSITION | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-08-04 | — | — | US | claimed |
| CN-105713166-A | Hard polyurethane foam containing organic-inorganic hybrid material and preparation method thereof | 中国石油化工股份有限公司 | 2016-06-29 | — | — | CN | claimed |
| US-9273175-B2 | Tertiary amine composition and method for making the composition | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-03-01 | — | — | US | claimed |
| CN-103772635-B | A kind of preparation method of marine oil and gas transport pipe lagging material | China Petroleum Chemical Co (CN) | 2016-01-06 | — | — | CN | claimed |
| CN-103772635-A | Preparation method of thermal insulation material for marine oil gas transportation pipeline | CHINA PETROLEUM & CHEMICAL | 2014-05-07 | — | — | CN | claimed |
| US-8580864-B2 | Trimer catalysts with improved processability and surface cure | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-11-12 | — | — | US | claimed |
| US-8530534-B2 | Trimerization catalysts from sterically hindered salts | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-09-10 | — | — | US | claimed |
| US-12624180-B2 | In-situ formation of low density thermoplastic polyurethane flexible foams | HUNTSMAN INTERNATIONAL LLC | 2026-05-12 | — | — | US | disclosed |
| EP-0143396-A2 | Crystallite suspensions of crystalline, ethylenically unsaturated polyesters and polyhydroxyl compounds, process for their preparation and their use in preparating polyurethanes or polymers containing polyurethane groups | BASF Aktiengesellschaft (DE) | 1985-06-05 | — | — | EP | disclosed |
| US-4402980-A | FUNGICIDES; WOOD PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624180-B2 | In-situ formation of low density thermoplastic polyurethane flexible foams | XRCC6, INTS6, OGG1 | ALDH1A1 3630/4885HSD17B10 2954/4885MAPT 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.