SCHEMBL3197544

SCHEMBL3197544

CCCCCCCCCCCCCCCCCCC(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@@H](C)O

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.52
MEN1 O00255 1/20 0.48
FAAH O00519 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
CES1 P23141 3/20 0.45
MAPT P10636 1/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3185746 1.00 CES2 (0.52) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL3196682 1.00 CES2 (0.52) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL18953029 1.00 CES2 (0.52) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL27822594 0.98 CES2 (0.48) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL3185732 0.98 CES2 (0.48) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL30576670 0.92 CES2 (0.41) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL9388696 0.92 CES2 (0.50) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL11784529 0.92 CES2 (0.59) CES2CES1
SCHEMBL11201948 0.90 CES2 (0.57) CES2MEN1FAAHMAPK1KMT2A
SCHEMBL9465217 0.88 CES2 (0.59) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163049-B2 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders PIERRE FABRE DERMO-COSMETIQUE (FR) 2015-10-20 US disclosed
EP-2266580-B1 Medicament comprising an alkyl-rhamnose monomer for the treatment of inflammatory disorders FABRE PIERRE DERMO COSMETIQUE (FR) 2014-03-26 EP disclosed
EP-1682158-B1 Cosmetic compositions comprising at least a rhamnose monomer for the cosmetic treatment of skins FABRE PIERRE DERMO COSMETIQUE (FR) 2011-05-25 EP disclosed
EP-2266580-A1 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders Pierre Fabre Dermo-Cosmétique (FR) 2010-12-29 EP disclosed
US-20100069311-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS HOULMONT JEAN-PHILIPPE 2010-03-18 US disclosed
US-7666847-B2 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders PIERRE FABRE DERMO-COSMETIQUE (FR) 2010-02-23 US disclosed
US-20070134187-A1 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders CENTRE NATIONAL DE LA RECHESRCHE SCIENTIFIQUE (CNRS) (FR) 2007-06-14 US disclosed
EP-1682158-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS Pierre Fabre Dermo-Cosmetique (FR) 2006-07-26 EP disclosed
WO-2005041983-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS PIERRE FABRE DERMO-COSMETIQUE (FR) 2005-05-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069311-A1 MEDICAMENT COMPRISING A REDUCING ALKYL-SUGAR MONOMER FOR THE TREATMENT OF INFLAMMATORY DISORDERS UGCG, UGGT1, TLR6 CES2 665/4885MEN1 3713/4885FAAH 181/4885
US-20070134187-A1 Medicament comprising a reducing alkyl-sugar monomer for the treatment of inflammatory disorders UGCG, TLR6, CD68 CES2 949/4885MEN1 3662/4885FAAH 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.