Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 4/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.62 |
| ▸ | SNCA | P37840 | 4/20 | 0.58 |
| ▸ | IKBKB | O14920 | 2/20 | 0.58 |
| ▸ | CHUK | O15111 | 2/20 | 0.58 |
| ▸ | IKBKG | Q9Y6K9 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
| ▸ | JUN | P05412 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198236 | 1.00 | GLO1 (0.62) | GLO1ABL1SNCAIKBKBCHUK | |
| SCHEMBL3208339 | 0.82 | GLO1 (0.71) | GLO1ABL1SNCAIKBKBCHUK | |
| SCHEMBL3208354 | 0.82 | GLO1 (0.71) | GLO1ABL1SNCAIKBKBCHUK | |
| SCHEMBL3208332 | 0.82 | GLO1 (0.71) | GLO1ABL1SNCAIKBKBCHUK | |
| SCHEMBL3222176 | 0.81 | APP (0.74) | GLO1SNCAMAPTAPPNFKB1 | |
| SCHEMBL3222154 | 0.81 | APP (0.74) | GLO1SNCAMAPTAPPNFKB1 | |
| SCHEMBL7194289 | 0.81 | SNCA (0.88) | GLO1ABL1SNCAIKBKBCHUK | |
| SCHEMBL8854590 | 0.80 | APP (0.74) | MAPTAPPNFKB1ALOX5STAT3 | |
| SCHEMBL4463365 | 0.78 | SNCA (0.79) | GLO1ABL1SNCAIKBKBCHUK | |
| SCHEMBL708383 | 0.78 | XDH (0.62) | MAPTAPPALOX5NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962674-B2 | Curcumin derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | disclosed |
| EP-2123637-A1 | NOVEL CURCUMIN DERIVATIVE | Tokyo Institute of Technology (JP) | 2009-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | GLO1 705/4885ABL1 4840/4885SNCA 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.