Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5672462 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL16874960 | 1.00 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL17997014 | 0.93 | ALDH1A1 (0.64) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL564467 | 0.89 | ALDH1A1 (0.64) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL10411833 | 0.87 | ALDH1A1 (0.59) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL14879973 | 0.86 | ALDH1A1 (0.56) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL17997021 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL232719 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL14638635 | 0.85 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA | |
| SCHEMBL26809029 | 0.85 | GAA (0.50) | ALDH1A1CYP3A4CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683041-B2 | Microgel particles for the delivery of bioactive materials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-03-23 | — | — | US | disclosed |
| US-7247384-B2 | tip coated with a monolayer of ethylene glycol derivatives resists the adsorption of proteins | THE UNIVERSITY OF HOUSTON (US) | 2007-07-24 | — | — | US | disclosed |
| US-20060223776-A1 | Microgel particles for the delivery of bioactive materials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-05 | — | — | US | disclosed |
| US-7056901-B2 | Microgel particles for the delivery of bioactive materials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1490083-A1 | MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS | The Regents of the University of California (US) | 2004-12-29 | — | — | EP | disclosed |
| US-20040213910-A1 | tip coated with a monolayer of ethylene glycol derivatives resists the adsorption of proteins | UNIVERSITY OF HOUSTON (US) | 2004-10-28 | — | — | US | disclosed |
| US-20030211158-A1 | Microgel particles for the delivery of bioactive materials | UNITED STATES DEPARTMENT OF ENERGY | 2003-11-13 | — | — | US | disclosed |
| WO-2003082316-A1 | MICROGEL PARTICLES FOR THE DELIVERY OF BIOACTIVE MATERIALS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030211158-A1 | Microgel particles for the delivery of bioactive materials | CTSE, CHMP4B, GAA | ALDH1A1 2991/4885CYP3A4 4661/4885CYP2C9 4467/4885 |
| US-20060223776-A1 | Microgel particles for the delivery of bioactive materials | CTSE, CHMP4B, GAA | ALDH1A1 2991/4885CYP3A4 4661/4885CYP2C9 4467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.