SCHEMBL564467

SCHEMBL564467

COCCS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.64
CYP3A4 P08684 1/20 0.64
CYP2C9 P11712 1/20 0.64
CYP2C19 P33261 1/20 0.64
LMNA P02545 3/20 0.56
HPGD P15428 1/20 0.56
HTT P42858 1/20 0.56
KMT2A Q03164 4/20 0.54
NPC1 O15118 1/20 0.54
LOX P28300 1/20 0.51
MEN1 O00255 1/20 0.47
GAA P10253 2/20 0.47
PAX8 Q06710 1/20 0.47
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16874960 0.89 ALDH1A1 (0.56) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL5672462 0.89 ALDH1A1 (0.56) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL3198374 0.89 ALDH1A1 (0.56) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL4098679 0.89 ALDH1A1 (0.71) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL17997014 0.84 ALDH1A1 (0.64) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL64436 0.83 ALDH1A1 (0.63) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL41372 0.83 ALDH1A1 (0.82) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL8521424 0.82 LOX (0.50) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL14374993 0.82 ALDH1A1 (0.62) ALDH1A1CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL1939147 0.82 PLCG1 (0.55) ALDH1A1LMNAHPGDKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10287313-B2 RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2019-05-14 US claimed
EP-2748176-B1 IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIV (CA) 2019-04-17 EP claimed
US-20160340382-A1 RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2016-11-24 US claimed
EP-2334692-B1 RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS UNIV MCGILL (CA) 2016-04-13 EP claimed
US-9249175-B2 RNA monomers containing O-acetal levulinyl ester groups and their use in RNA microarrays THE ROYAL INSTITUTE FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2016-02-02 US claimed
EP-2639307-B1 Single-stranded nucleic acid molecule having nitrogen-containing alicyclic skeleton BONAC CORP (JP) 2015-03-04 EP claimed
US-20120178638-A1 RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-07-12 US claimed
EP-2334692-A1 RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS The Royal Institution for the Advancement of Learning / McGill University (CA) 2011-06-22 EP claimed
WO-2010025566-A1 RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) 2010-03-11 WO claimed
EP-3862431-B1 METHOD FOR PRODUCING HAIRPIN SINGLE-STRAND RNA MOLECULES TORAY INDUSTRIES (JP) 2024-06-26 EP disclosed
US-20240167033-A1 METHOD OF PRODUCING HAIRPIN SINGLE-STRANDED RNA MOLECULE TORAY INDUSTRIES, INC. (JP) 2024-05-23 US disclosed
WO-2024106539-A1 LIGAND CONJUGATE SUBSTANCE, NUCLEIC ACID CONTAINING SAME, AND USE THEREOF 株式会社ボナック 2024-05-23 WO disclosed
WO-2024101446-A1 MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME ルクサナバイオテク株式会社 2024-05-16 WO disclosed
EP-3659609-B1 THERAPEUTIC AGENT FOR FIBROSIS KYORIN SEIYAKU KK (JP) 2024-05-08 EP disclosed
US-20080102281-A1 MULTIFUNCTIONAL SELF-DECONTAMINATING SURFACE COATING THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-05-01 US disclosed
US-7339015-B2 Multifunctional self-decontaminating surface coating THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2008-03-04 US disclosed
US-7294716-B2 Process for preparing isomerically pure prodrugs of proton pump inhibitors ALLERGAN, INC. (US) 2007-11-13 US disclosed
WO-2007064291-A1 METHOD AND COMPOUNDS FOR RNA SYNTHESIS CHATTOPADHYAYA JYOTI (SE) 2007-06-07 WO disclosed
WO-2007064291-A1 METHOD AND COMPOUNDS FOR RNA SYNTHESIS CHATTOPADHYAYA JYOTI (SE) 2007-06-07 WO disclosed
US-20070122438-A1 Multifunctional self-decontaminating surface coating THE GOVERNMENT OF THE UNITED STATES, AS RESPRESENTED BY THE SECRETARY OF THE NAVY 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10287313-B2 RNA monomers containing 0-acetal levulinyl ester groups and their use in RNA microarrays EFTUD2, RNMT, NSUN2 ALDH1A1 199/4885CYP3A4 3560/4885CYP2C9 3723/4885
US-20160340382-A1 RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS EFTUD2, RNMT, RNGTT ALDH1A1 212/4885CYP3A4 3599/4885CYP2C9 3789/4885
US-20070122438-A1 Multifunctional self-decontaminating surface coating YWHAZ, EPCAM, LBR ALDH1A1 2502/4885CYP3A4 3092/4885CYP2C9 3016/4885
US-20120178638-A1 RNA MONOMERS CONTAINING O-ACETAL LEVULINYL ESTER GROUPS AND THEIR USE IN RNA MICROARRAYS EFTUD2, RNMT, RNGTT ALDH1A1 212/4885CYP3A4 3599/4885CYP2C9 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.