Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.45 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 3/20 | 0.40 |
| ▸ | PFKFB4 | Q16877 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856131 | 0.96 | KDM4E (0.42) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1851302 | 0.91 | KDM4E (0.46) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1849782 | 0.85 | KDM4C (0.43) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL3209831 | 0.81 | ROCK1 (0.43) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1850776 | 0.79 | KDM4C (0.46) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1851474 | 0.79 | KDM4E (0.47) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1851004 | 0.78 | KDM4E (0.48) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1855326 | 0.76 | KDM4E (0.44) | KDM4EKDM6BKDM5CKDM4CKDM2A | |
| SCHEMBL1849813 | 0.75 | PRKDC (0.44) | SMN1; SMN2NPC1HPGDRAB9ATP53 | |
| SCHEMBL1853424 | 0.73 | KDM4E (0.48) | KDM4EKDM6BKDM5CKDM4CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041891-A1 | AMIDE COMPOUND | GPR52, GPR132, NR5A2 | KDM4E 3467/4885KDM6B 3232/4885KDM5C 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.