Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.39 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774381 | 0.86 | CYP3A4 (0.43) | CYP3A4CYP2A6MAPTMAOBLOXL2 | |
| SCHEMBL5685999 | 0.85 | SMN1; SMN2 (0.59) | CYP3A4CYP2A6MAPTPOLBMAPK1 | |
| SCHEMBL10347560 | 0.83 | MAPT (0.56) | CYP3A4CYP2A6MAPTMAOBLOXL2 | |
| SCHEMBL30663731 | 0.83 | MAPT (0.56) | CYP3A4CYP2A6MAPTMAOBLOXL2 | |
| SCHEMBL4090880 | 0.82 | SMN1; SMN2 (0.50) | CYP3A4CYP2A6MAPTMAOBPOLB | |
| SCHEMBL19038909 | 0.82 | CYP3A4 (0.57) | CYP3A4CYP2A6MAPTMAOBLOXL2 | |
| SCHEMBL10517952 | 0.82 | MAOB (0.56) | CYP3A4CYP2A6MAPTMAOBMAPK1 | |
| Hydrochloric Acid SCHEMBL21694039 | 0.81 | MAPT (0.55) | CYP3A4CYP2A6MAPTMAOBLOXL2 | |
| SCHEMBL19616353 | 0.80 | MAPT (0.48) | CYP3A4CYP2A6MAPTMAOBLOXL2 | |
| SCHEMBL10638648 | 0.79 | RAB9A (0.51) | CYP3A4CYP2A6MAPTPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9333150-B2 | Dental restorative materials based on polymerizable azides and alkynes | IVOCLAR VIVADENT AG (LI) | 2016-05-10 | — | — | US | disclosed |
| US-9333150-B2 | Dental restorative materials based on polymerizable azides and alkynes | IVOCLAR VIVADENT AG (LI) | 2016-05-10 | — | — | US | disclosed |
| US-20140171536-A1 | Dental Restorative Materials Based on Polymerizable Azides and Alkynes | IVOCLAR VIVADENT AG (LI) | 2014-06-19 | — | — | US | disclosed |
| US-20140171536-A1 | Dental Restorative Materials Based on Polymerizable Azides and Alkynes | IVOCLAR VIVADENT AG (LI) | 2014-06-19 | — | — | US | disclosed |
| EP-2743267-A1 | Dental materials based on polymerisable azides and alkenes | Ivoclar Vivadent AG (LI) | 2014-06-18 | — | — | EP | disclosed |
| US-8101238-B2 | Polymeric materials via click chemistry | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-01-24 | — | — | US | disclosed |
| US-8101238-B2 | Polymeric materials via click chemistry | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-01-24 | — | — | US | disclosed |
| US-20100029888-A1 | Click-Reaction Crosslinkable Multicomponent Silicone Compositions | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |
| US-20080311412-A1 | Polymeric Materials Via Click Chemistry | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-18 | — | — | US | disclosed |
| US-20080311412-A1 | Polymeric Materials Via Click Chemistry | THE SCRIPPS RESEARCH INSTITUTE (US) | 2008-12-18 | — | — | US | disclosed |
| EP-0249567-A2 | Propargyloxybenzene derivatives, their preparation and fungicidal compositions containing them | RHONE-POULENC AGROCHIMIE (FR) | 1987-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140171536-A1 | Dental Restorative Materials Based on Polymerizable Azides and Alkynes | PRXL2A, CNPY2, CDYL | CYP3A4 4366/4885CYP2A6 3479/4885MAPT 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.