(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL3198659

C(=C/c1ccccc1)\c1ccccc1.c1cnnnc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.54
CYP11B2 P19099 1/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAOB P27338 4/20 0.50
MAOA P21397 3/20 0.48
NFE2L2 Q16236 2/20 0.48
CYP19A1 P11511 2/20 0.48
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
ADRA2A P08913 1/20 0.45
NISCH Q9Y2I1 1/20 0.45
CHAT P28329 2/20 0.44
GRM4 Q14833 2/20 0.44
HDAC6 Q9UBN7 1/20 0.44
TRPA1 O75762 2/20 0.43
RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL529988 1.00 CYP11B1 (0.54) CYP11B1CYP11B2MEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL7755679 1.00 CYP11B1 (0.54) CYP11B1CYP11B2MEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL27808110 0.97 CYP11B1 (0.52) CYP11B1CYP11B2MEN1KMT2AMAOB
SCHEMBL28025874 0.86 CYP11B1 (0.47) CYP11B1CYP11B2MEN1KMT2AMAOB
SCHEMBL9615911 0.86 MAOB (0.42) CYP11B1CYP11B2MEN1KMT2AMAOB
Styrene SCHEMBL1726001 0.80 ALDH1A1 (0.67) CYP11B1CYP11B2MEN1KMT2AMAOB
Styrene SCHEMBL7045807 0.80 ALDH1A1 (0.67) CYP11B1CYP11B2MEN1KMT2AMAOB
Benzaldehyde SCHEMBL28689897 0.80 ALDH1A1 (0.67) MEN1KMT2AKDM4EALDH1A1TRPA1
(Z)-1,2-Diphenylethene SCHEMBL27619643 0.80 MAOB (0.65) CYP11B1CYP11B2MEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.80 MAOB (0.73) CYP11B1CYP11B2MEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227099-B1 PROCESS FOR PRODUCING TYRES PROVIDED WITH AUXILIARY COMPONENTS AND TYRE HAVING AN AUXILIARY COMPONENT PIRELLI (IT) 2020-11-18 EP claimed
EP-3227099-A1 PROCESS FOR PRODUCING TYRES PROVIDED WITH AUXILIARY COMPONENTS AND TYRE HAVING AN AUXILIARY COMPONENT Pirelli Tyre S.p.A. (IT) 2017-10-11 EP claimed
EP-2794288-B1 COLOURED TYRE PORTIONS BRIDGESTONE CORP (JP) 2016-06-08 EP claimed
US-20150005418-A1 COLOURED TYRE PORTIONS BRIDGESTONE CORPORATION (JP) 2015-01-01 US claimed
WO-2023126375-A1 MARKING COMPOSITION FOR APPLICATION ON A SPORTS PROJECTILE GROUNDTOUCH GMBH (DE) 2023-07-06 WO disclosed
EP-3227099-B1 PROCESS FOR PRODUCING TYRES PROVIDED WITH AUXILIARY COMPONENTS AND TYRE HAVING AN AUXILIARY COMPONENT PIRELLI (IT) 2020-11-18 EP disclosed
EP-3227099-A1 PROCESS FOR PRODUCING TYRES PROVIDED WITH AUXILIARY COMPONENTS AND TYRE HAVING AN AUXILIARY COMPONENT Pirelli Tyre S.p.A. (IT) 2017-10-11 EP disclosed
CN-107000347-A Method for producing a tyre with auxiliary components and tyre with auxiliary components 倍耐力轮胎股份公司 2017-08-01 CN disclosed
EP-2794288-B1 COLOURED TYRE PORTIONS BRIDGESTONE CORP (JP) 2016-06-08 EP disclosed
US-20150322070-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 AUSPEX PHARMACEUTICALS, INC. 2015-11-12 US disclosed
US-20150005418-A1 COLOURED TYRE PORTIONS BRIDGESTONE CORPORATION (JP) 2015-01-01 US disclosed
US-20100227788-A1 Granulate of a Sensitive Ingredient of a Washing or Cleaning Agent HENKEL AG & CO. KGAA (DE) 2010-09-09 US disclosed
US-5279772-A Liquid detergents containing specifically disulfonated dibenzofuranyl-biphenyls as flourescent whitening agents CIBA-GEIGY CORPORATION (US) 1994-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150322070-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 JAK2, JAK3, PAK3 CYP11B1 3770/4885CYP11B2 3763/4885MEN1 4552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.