(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL7755679

C(=C/c1ccccc1)\c1ccccc1.c1cnnnc1.c1cnnnc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.54
CYP11B2 P19099 1/20 0.54
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
MAOB P27338 4/20 0.50
MAOA P21397 3/20 0.48
NFE2L2 Q16236 2/20 0.48
CYP19A1 P11511 2/20 0.48
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
ADRA2A P08913 1/20 0.45
NISCH Q9Y2I1 1/20 0.45
CHAT P28329 2/20 0.44
GRM4 Q14833 2/20 0.44
HDAC6 Q9UBN7 1/20 0.44
TRPA1 O75762 2/20 0.43
RELA Q04206 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL529988 1.00 CYP11B1 (0.54) CYP11B1CYP11B2MEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL3198659 1.00 CYP11B1 (0.54) CYP11B1CYP11B2MEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL27808110 0.97 CYP11B1 (0.52) CYP11B1CYP11B2MEN1KMT2AMAOB
SCHEMBL28025874 0.86 CYP11B1 (0.47) CYP11B1CYP11B2MEN1KMT2AMAOB
SCHEMBL9615911 0.86 MAOB (0.42) CYP11B1CYP11B2MEN1KMT2AMAOB
Styrene SCHEMBL1726001 0.80 ALDH1A1 (0.67) CYP11B1CYP11B2MEN1KMT2AMAOB
Styrene SCHEMBL7045807 0.80 ALDH1A1 (0.67) CYP11B1CYP11B2MEN1KMT2AMAOB
Benzaldehyde SCHEMBL28689897 0.80 ALDH1A1 (0.67) MEN1KMT2AKDM4EALDH1A1TRPA1
(Z)-1,2-Diphenylethene SCHEMBL27619643 0.80 MAOB (0.65) CYP11B1CYP11B2MEN1KMT2AMAOB
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.80 MAOB (0.73) CYP11B1CYP11B2MEN1KMT2AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0599383-B1 Silver halide photographic elements containing furan or pyrrole substituted dye compounds EASTMAN KODAK CO (US) 2001-02-28 EP disclosed
EP-0599384-B1 Dye compounds and photographic elements containing such dyes EASTMAN KODAK CO (US) 2000-01-19 EP disclosed
EP-0599381-B1 Dye compounds and silver halide photographic elements containing such dyes EASTMAN KODAK CO (US) 2000-01-19 EP disclosed
US-5674674-A PHOTOGRAPHIC ELEMENT HAVING SILVER CHLORIDE/CHLOROIODIDE EMULSION SENSITIZED WITH CYANINE DYE EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
US-5492802-A SENSITIZING CYANINE DYE EASTMAN KODAK COMPANY (US) 1996-02-20 US disclosed
EP-0451816-B1 Sensitizing dye for photographic materials EASTMAN KODAK CO (US) 1995-07-05 EP disclosed
US-5418126-A ELEMENT COMPRISING A LIGHT SENSITIVE EMULSION CONTAINING A SENSITIZING DYE EASTMAN KODAK COMPANY (US) 1995-05-23 US disclosed
US-5354651-A Cyanine dyes as sensitizers; antisoilant EASTMAN KODAK COMPANY (US) 1994-10-11 US disclosed
EP-0599383-A1 Furan or pyrrole substituted dye compounds and silver halide photographic elements containing such dyes EASTMAN KODAK COMPANY (US) 1994-06-01 EP disclosed
EP-0599384-A1 Dye compounds and photographic elements containing such dyes EASTMAN KODAK COMPANY (US) 1994-06-01 EP disclosed
EP-0599381-A1 Dye compounds and silver halide photographic elements containing such dyes EASTMAN KODAK COMPANY (US) 1994-06-01 EP disclosed
EP-0599382-A1 hydroxyarylacyl dye compounds and silver halide photographic elements containing such dyes EASTMAN KODAK COMPANY (US) 1994-06-01 EP disclosed
US-5316904-A Cationic cyanine sensitizers in color photography EASTMAN KODAK COMPANY (US) 1994-05-31 US disclosed
US-5135845-A Fluorine-substitued cyanine dyes; antisoilants; black and white and color photography EASTMAN KODAK COMPANY (US) 1992-08-04 US disclosed
EP-0451816-A1 Sensitizing dye for photographic materials EASTMAN KODAK COMPANY (US) 1991-10-16 EP disclosed