⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463692 | 0.65 | — | — | |
| SCHEMBL7009725 | 0.65 | — | — | |
| SCHEMBL3190159 | 0.58 | — | — | |
| SCHEMBL1852820 | 0.55 | — | — | |
| SCHEMBL10871904 | 0.54 | — | — | |
| SCHEMBL409272 | 0.54 | — | — | |
| SCHEMBL24623113 | 0.53 | — | — | |
| SCHEMBL23008968 | 0.53 | EED (0.33) | — | |
| SCHEMBL898580 | 0.51 | OPRM1 (0.33) | — | |
| SCHEMBL11510486 | 0.51 | ADH1C (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41149-E1 | Stereoisomerically pure 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid or a pharmaceutically acceptable salt thereof; antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |
| US-6031102-A | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| EP-0341493-B1 | Optically active pyridonecarboxylic acid derivatives | DAIICHI SEIYAKU CO (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5767127-A | BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5696132-A | MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| US-5587386-A | BACTERICIDES, MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| US-5436253-A | Fungicides of 4-oxo-1,4-dihydroquinoline-7-carboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0394553-B1 | Use of fluorine containing pyridone carboxylic acid derivatives for preparing a medicament for the treatment of HIV infections | DAIICHI SEIYAKU CO (JP) | 1995-06-21 | — | — | EP | disclosed |
| EP-0593766-A1 | PYRIDONECARBOXYLIC ACID DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| EP-0470252-A1 | ANTI-HIV DRUG | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |
| EP-0394553-A2 | Use of fluorine containing pyridone carboxylic acid derivatives for preparing a medicament for the treatment of HIV infections | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0341493-A2 | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |