Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467901 | 1.00 | OPRM1 (0.33) | OPRM1ADH1CADH1AALDH1A1SLC18A3 | |
| SCHEMBL865400 | 1.00 | OPRM1 (0.33) | OPRM1ADH1CADH1AALDH1A1SLC18A3 | |
| SCHEMBL847116 | 1.00 | OPRM1 (0.33) | OPRM1ADH1CADH1AALDH1A1SLC18A3 | |
| SCHEMBL663435 | 1.00 | OPRM1 (0.33) | OPRM1ADH1CADH1AALDH1A1SLC18A3 | |
| SCHEMBL17429935 | 1.00 | OPRM1 (0.33) | OPRM1ADH1CADH1AALDH1A1SLC18A3 | |
| SCHEMBL21985216 | 0.96 | ADH1C (0.38) | OPRM1ADH1CADH1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6657602 | 0.93 | OPRM1 (0.32) | OPRM1ADH1CADH1A | |
| SCHEMBL11501607 | 0.92 | ADH1C (0.33) | ADH1CADH1AALDH1A1 | |
| SCHEMBL11510486 | 0.92 | ADH1C (0.33) | ADH1CADH1AALDH1A1 | |
| SCHEMBL11465502 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758333-B1 | INTERMEDIATES IN PHARMACEUTICAL CAMPTOTHECIN PREPARATION | OSI PHARM INC (US) | 2004-03-03 | — | — | EP | claimed |
| US-5491237-A | Intermediates in pharmaceutical camptothecin preparation | GLAXO WELLCOME INC. (US) | 1996-02-13 | — | — | US | claimed |
| US-12583851-B2 | Heteroaryl-substituted pyrazine derivatives as pesticides | ELANCO ANIMAL HEALTH GMBH (DE) | 2026-03-24 | — | — | US | disclosed |
| US-20250122152-A1 | KAT6 Inhibitors | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-17 | — | — | US | disclosed |
| WO-2025068943-A1 | KAT6 INHIBITORS | BEIGENE SWITZERLAND GMBH (CH) | 2025-04-03 | — | — | WO | disclosed |
| US-20230242513-A1 | NOVEL HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-08-03 | — | — | US | disclosed |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230142119-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-11 | — | — | US | disclosed |
| EP-4172154-A1 | NOVEL HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | Bayer Animal Health GmbH (DE) | 2023-05-03 | — | — | EP | disclosed |
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-01-26 | — | — | US | disclosed |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-09-29 | — | — | US | disclosed |
| US-4965364-A | OLEFIN, CHIRAL LIGAND, ORGANIC SOLVENT, WATER, AMINE OXIDE AND OSMIUM-CONTAINING COMPOUND | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4871855-A | Ligand-accelerated catalytic asymmetric dihydroxylation using dihydroquinidine and dihydroquinidine esters as ligands | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-10-03 | — | — | US | disclosed |
| WO-1989006225-A1 | LIGAND-ACCELERATED CATALYTIC ASYMMETRIC DIHYDROXYLATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1989-07-13 | — | — | WO | disclosed |
| US-4268455-A | Chelating tertiary amino metal amides | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-05-19 | — | — | US | disclosed |
| US-4165330-A | REACTION OF ORGANOLITHIUM-CHELATE COMPLEX AND PROCHIRAL UNSATURATED CARBONYL COMPOUNDS | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-08-21 | — | — | US | disclosed |
| US-4134938-A | ETHYLENE, STYRENE POLYMER-LITHIUM-CHELATING POLYAMINE COMPLEX | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4108921-A | Process for polymer lithiation in graft polymerization | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-08-22 | — | — | US | disclosed |
| US-4107238-A | THERMOELASTOMERS, ISOBUTYLENE-CONJUGATED DIENE COPOLYMER, STYRENE | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4078019-A | Process for polymer lithiation in graft polymerization | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12583851-B2 | Heteroaryl-substituted pyrazine derivatives as pesticides | CBR3, CYCS, CWC15 | OPRM1 931/4885ADH1C 446/4885ADH1A 3014/4885 |
| US-20230142119-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | OPRM1 2187/4885ADH1C 84/4885ADH1A 217/4885 |
| US-20230242513-A1 | NOVEL HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | DDT, PRXL2A, CAT | OPRM1 1972/4885ADH1C 2653/4885ADH1A 3240/4885 |
| US-20230023326-A1 | HETEROARYL-SUBSTITUTED PYRAZINE DERIVATIVES AS PESTICIDES | DDT, PRXL2A, CAT | OPRM1 1949/4885ADH1C 2525/4885ADH1A 3221/4885 |
| US-20220306578-A1 | TETRACYCLIC COMPOUND | ALK, TTR, ACVR1 | OPRM1 2187/4885ADH1C 84/4885ADH1A 217/4885 |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | OPRM1 2219/4885ADH1C 4389/4885ADH1A 4403/4885 |
| US-20250122152-A1 | KAT6 Inhibitors | KAT6A, KAT6B, KAT7 | OPRM1 2917/4885ADH1C 3082/4885ADH1A 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.