Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.31 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10536 | 0.81 | DYRK1A (0.38) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL31568071 | 0.81 | PARP1 (0.40) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL311558 | 0.73 | PARP1 (0.40) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL196912 | 0.73 | PARP1 (0.42) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL3232202 | 0.71 | PARP1 (0.41) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL196737 | 0.69 | PARP1 (0.56) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL312428 | 0.69 | PARP1 (0.43) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL1445123 | 0.69 | PDPK1 (0.41) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL1651016 | 0.69 | PARP1 (0.53) | PARP1SMN1; SMN2PDPK1CA12ALOX15 | |
| SCHEMBL4130388 | 0.69 | PARP1 (0.56) | PARP1SMN1; SMN2PDPK1CA12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6092934-A | — | — | None | — | — | JP | disclosed |
| US-20100041722-A1 | ORGANIC COMPOUNDS | HU QI-YING | 2010-02-18 | — | — | US | disclosed |
| JP-H0692934-A | COMPOUND USEFUL IN PRODUCING PIPERAZINE DERIVATIVE AND SALT THEREOF | DUPHAR INTERNATL RES BV | 1994-04-05 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041722-A1 | ORGANIC COMPOUNDS | CYP11B1, CYP11B2, CYP21A2 | PARP1 3522/4885SMN1; SMN2 4518/4885PDPK1 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.