Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196912 | 0.77 | PARP1 (0.42) | PARP1SMN1; SMN2CA12CA9PDPK1 | |
| SCHEMBL3232202 | 0.76 | PARP1 (0.41) | PARP1SMN1; SMN2CA12CA9PDPK1 | |
| SCHEMBL1445123 | 0.74 | PDPK1 (0.41) | PARP1SMN1; SMN2CA12CA9PDPK1 | |
| SCHEMBL1193119 | 0.74 | PARP1 (0.39) | PARP1MAPTKDM4EALDH1A1IP6K1 | |
| SCHEMBL29804759 | 0.74 | PARP1 (0.39) | PARP1MAPTKDM4EALDH1A1IP6K1 | |
| SCHEMBL196737 | 0.74 | PARP1 (0.56) | PARP1SMN1; SMN2CA12CA9PDPK1 | |
| SCHEMBL312428 | 0.74 | PARP1 (0.43) | PARP1SMN1; SMN2CA12CA9PDPK1 | |
| SCHEMBL30036694 | 0.74 | PARP1 (0.43) | PARP1SMN1; SMN2CA12CA9PDPK1 | |
| SCHEMBL1019602 | 0.74 | QPCT (0.42) | PARP1SMN1; SMN2CA12CA9PDPK1 | |
| SCHEMBL8668 | 0.74 | PARP1 (0.56) | PARP1SMN1; SMN2CA12CA9PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200292-B1 | 1H-BENZO[D]IMIDAZOLE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS | BRISTOL MYERS SQUIBB CO (US) | 2024-11-13 | — | — | EP | claimed |
| US-12128026-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2024-10-29 | — | — | US | disclosed |
| US-20240262838-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2024-08-08 | — | — | US | disclosed |
| EP-3286164-B1 | SELECTIVE ANDROGEN RECEPTOR DEGRADER (SARD) LIGANDS AND METHODS OF USE THEREOF | ONCTERNAL THERAPEUTICS INC (US) | 2024-05-29 | — | — | EP | disclosed |
| CN-114644638-B | Nitrogen-containing heterocyclic compound and application thereof | 广州华睿光电材料有限公司 | 2024-04-23 | — | — | CN | disclosed |
| US-11873282-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230416228-A1 | AGENTS FOR THE TREATMENT OF DISEASES BY INHIBITION OF FOXO1 | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEWYORK | 2023-12-28 | — | — | US | disclosed |
| CN-114621237-B | Organic compounds, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-11648234-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2023-05-16 | — | — | US | disclosed |
| CN-107709290-B | Selective Androgen Receptor Degrader (SARD) ligands and methods of use thereof | GTX公司 | 2023-02-28 | — | — | CN | disclosed |
| EP-2066316-A1 | AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION (US) | 2009-06-10 | — | — | EP | disclosed |
| WO-2008033447-A1 | AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |
| US-20080070888-A1 | AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION | 2008-03-20 | — | — | US | disclosed |
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | SAI NIPPON PRINTING CO., LTD. (JP) | 2007-11-22 | — | — | US | disclosed |
| WO-2005108374-A1 | INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-11-17 | — | — | WO | disclosed |
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| US-3988155-A | CYANINE SENSITIZING DYES | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-26 | — | — | US | disclosed |
| US-3985563-A | Silver halide photographic emulsion | FUJI PHOTO FILM CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230416228-A1 | AGENTS FOR THE TREATMENT OF DISEASES BY INHIBITION OF FOXO1 | FOXO1, FOXO3, GCKR | PARP1 1389/4885SMN1; SMN2 495/4885CA12 4667/4885 |
| US-11648234-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use | AR, BRCA1, FSHR | PARP1 181/4885SMN1; SMN2 186/4885CA12 4341/4885 |
| US-20070269664-A1 | Gas Barrier Laminated Film and Process for Producing the Same | CDH1, VIL1, TET1 | PARP1 1997/4885SMN1; SMN2 3275/4885CA12 646/4885 |
| US-20080070888-A1 | AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | OPRD1, OPRK1, OPRL1 | PARP1 3378/4885SMN1; SMN2 1682/4885CA12 4672/4885 |
| US-20240262838-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | NPR1, NPR3, NUCB2 | PARP1 1264/4885SMN1; SMN2 2588/4885CA12 361/4885 |
| US-12128026-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | AR, AHR, BRDT | PARP1 92/4885SMN1; SMN2 765/4885CA12 4816/4885 |
| US-11873282-B2 | Selective androgen receptor degrader (SARD) ligands and methods of use thereof | AR, AHR, BRDT | PARP1 92/4885SMN1; SMN2 765/4885CA12 4816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.