Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.78 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.68 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.67 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | F3 | P13726 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922397 | 1.00 | OXER1 (0.78) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31957 | 1.00 | OXER1 (0.78) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31996 | 1.00 | OXER1 (0.78) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31967 | 1.00 | OXER1 (0.78) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31999 | 1.00 | OXER1 (0.78) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31928 | 0.96 | OXER1 (0.80) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31955 | 0.96 | OXER1 (0.80) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31757 | 0.96 | OXER1 (0.80) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL31964 | 0.96 | OXER1 (0.80) | OXER1CMKLR1LTB4R2ALOX5MAPT | |
| SCHEMBL32029 | 0.96 | OXER1 (0.80) | OXER1CMKLR1LTB4R2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853437-B2 | Anti-inflammatory compounds | THE UNIVERSITY OF TOKYO (JP) | 2014-10-07 | — | — | US | disclosed |
| US-8853437-B2 | Anti-inflammatory compounds | THE UNIVERSITY OF TOKYO (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20120059061-A1 | NOVEL ANTI-INFLAMMATORY COMPOUNDS | THE UNIVERSITY OF TOKYO (JP) | 2012-03-08 | — | — | US | disclosed |
| US-20120059061-A1 | NOVEL ANTI-INFLAMMATORY COMPOUNDS | THE UNIVERSITY OF TOKYO (JP) | 2012-03-08 | — | — | US | disclosed |
| WO-2012026106-A1 | OPTICALLY ACTIVE NOVEL ANTI-INFLAMMATORY COMPOUND AND METHOD FOR PRODUCING SAME | 国立大学法人 東京大学 (JP) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059061-A1 | NOVEL ANTI-INFLAMMATORY COMPOUNDS | ALOX15, ALOX15B, ALOX12 | OXER1 174/4885CMKLR1 447/4885LTB4R2 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.